ConnectedAlign: a PPI network alignment method for identifying conserved protein complexes across multiple species

ConnectedAlign: a PPI network alignment method for identifying conserved protein complexes across multiple species

Abstract Background In bioinformatics, network alignment algorithms have been applied to protein-protein interaction (PPI) networks to discover evolutionary conserved substructures at the system level. However, most previous methods aim to maximize the similarity of aligned proteins in pairwise netw...

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Bibliographic Details
Main Authors: Jianliang Gao, Bo Song, Xiaohua Hu, Fengxia Yan, Jianxin Wang
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Bioinformatics
Subjects:
Network alignment
Big data
Graph data analysis
Online Access:http://link.springer.com/article/10.1186/s12859-018-2271-6

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