Collagen 1a1 Expression by Airway Macrophages Increases In Fibrotic ILDs and Is Associated With FVC Decline and Increased Mortality

Collagen 1a1 Expression by Airway Macrophages Increases In Fibrotic ILDs and Is Associated With FVC Decline and Increased Mortality

Within the Interstitial Lung Diseases (ILD), patients with idiopathic pulmonary fibrosis (IPF) and a subset of those with non-IPF fibrotic ILD have a distinct clinical phenotype of progression despite management. This group of patients has been collectively termed the progressive fibrotic phenotype...

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Bibliographic Details
Main Authors: Eliza Tsitoura, Athina Trachalaki, Eirini Vasarmidi, Semeli Mastrodemou, George A. Margaritopoulos, Maria Kokosi, Dionysios Fanidis, Apostolos Galaris, Vassilis Aidinis, Elizabeth Renzoni, Nikos Tzanakis, Athol U. Wells, Katerina M. Antoniou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
IPF
RA-ILD
NSIP
airway macrophages
SPP1
osteopontin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.645548/full

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