Population structure of Staphylococcus aureus from Trinidad & Tobago.
It has been shown previously that high rates of methicillin- and mupirocin-resistant Staphylococcus aureus exist in the Caribbean islands of Trinidad and Tobago, as well as a high prevalence of Panton-Valentine leukocidin-positive S. aureus. Beyond these studies, limited typing data have been publis...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3929661?pdf=render |
| _version_ | 1818145688810160128 |
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| author | Stefan Monecke Bettina Stieber Rashida Roberts Patrick Eberechi Akpaka Peter Slickers Ralf Ehricht |
| author_facet | Stefan Monecke Bettina Stieber Rashida Roberts Patrick Eberechi Akpaka Peter Slickers Ralf Ehricht |
| author_sort | Stefan Monecke |
| collection | DOAJ |
| description | It has been shown previously that high rates of methicillin- and mupirocin-resistant Staphylococcus aureus exist in the Caribbean islands of Trinidad and Tobago, as well as a high prevalence of Panton-Valentine leukocidin-positive S. aureus. Beyond these studies, limited typing data have been published. In order to obtain insight into the population structure not only of MRSA but also of methicillin-susceptible S. aureus, 294 clinical isolates collected in 2012/2013 were typed by microarray hybridisation. A total of 15.31% of the tested isolates were MRSA and 50.00% were PVL-positive. The most common MSSA strains were PVL-positive CC8-MSSA (20.41% of all isolates tested), PVL-positive CC152-MSSA (9.52%) and PVL-positive CC30-MSSA (8.84%) while the most common MRSA were ST239-MRSA-III&SCCmer (9.18%) and ST8-MRSA-IV, "USA300" (5.78%). 2.38% of characterised isolates belonged to distinct strains likely to be related to "Staphylococcus argenteus" lineages. The population structure of S. aureus isolates suggests an importation of strains from Africa, endemicity of PVL-positive MSSA (mainly CC8) and of ST239-MRSA-III, and a recent emergence of the PVL-positive CC8-MRSA-IV strain "USA300". |
| first_indexed | 2024-12-11T12:07:26Z |
| format | Article |
| id | doaj.art-db8bf93377dd4d8db6a4cbd2ac152c99 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-11T12:07:26Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-db8bf93377dd4d8db6a4cbd2ac152c992022-12-22T01:07:54ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0192e8912010.1371/journal.pone.0089120Population structure of Staphylococcus aureus from Trinidad & Tobago.Stefan MoneckeBettina StieberRashida RobertsPatrick Eberechi AkpakaPeter SlickersRalf EhrichtIt has been shown previously that high rates of methicillin- and mupirocin-resistant Staphylococcus aureus exist in the Caribbean islands of Trinidad and Tobago, as well as a high prevalence of Panton-Valentine leukocidin-positive S. aureus. Beyond these studies, limited typing data have been published. In order to obtain insight into the population structure not only of MRSA but also of methicillin-susceptible S. aureus, 294 clinical isolates collected in 2012/2013 were typed by microarray hybridisation. A total of 15.31% of the tested isolates were MRSA and 50.00% were PVL-positive. The most common MSSA strains were PVL-positive CC8-MSSA (20.41% of all isolates tested), PVL-positive CC152-MSSA (9.52%) and PVL-positive CC30-MSSA (8.84%) while the most common MRSA were ST239-MRSA-III&SCCmer (9.18%) and ST8-MRSA-IV, "USA300" (5.78%). 2.38% of characterised isolates belonged to distinct strains likely to be related to "Staphylococcus argenteus" lineages. The population structure of S. aureus isolates suggests an importation of strains from Africa, endemicity of PVL-positive MSSA (mainly CC8) and of ST239-MRSA-III, and a recent emergence of the PVL-positive CC8-MRSA-IV strain "USA300".http://europepmc.org/articles/PMC3929661?pdf=render |
| spellingShingle | Stefan Monecke Bettina Stieber Rashida Roberts Patrick Eberechi Akpaka Peter Slickers Ralf Ehricht Population structure of Staphylococcus aureus from Trinidad & Tobago. PLoS ONE |
| title | Population structure of Staphylococcus aureus from Trinidad & Tobago. |
| title_full | Population structure of Staphylococcus aureus from Trinidad & Tobago. |
| title_fullStr | Population structure of Staphylococcus aureus from Trinidad & Tobago. |
| title_full_unstemmed | Population structure of Staphylococcus aureus from Trinidad & Tobago. |
| title_short | Population structure of Staphylococcus aureus from Trinidad & Tobago. |
| title_sort | population structure of staphylococcus aureus from trinidad tobago |
| url | http://europepmc.org/articles/PMC3929661?pdf=render |
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