SARS-CoV-2 infects an in vitro model of the human developing pancreas through endocytosis

SARS-CoV-2 infects an in vitro model of the human developing pancreas through endocytosis

Summary: Recent studies showed that SARS-CoV-2 can infect adult human pancreas and trigger pancreatic damage. Here, using human fetal pancreas samples and 3D differentiation of human pluripotent cells into pancreatic endocrine cells, we determined that SARS-CoV-2 receptors ACE2, TMPRSS2, and NRP1 ar...

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Bibliographic Details
Main Authors: Wojciech J. Szlachcic, Agnieszka Dabrowska, Aleksandra Milewska, Natalia Ziojla, Katarzyna Blaszczyk, Emilia Barreto-Duran, Marek Sanak, Marcin Surmiak, Katarzyna Owczarek, Dariusz Grzanka, Julia Durzynska, Krzysztof Pyrc, Malgorzata Borowiak
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:iScience
Subjects:
Model organism
Virology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222008665

Internet

http://www.sciencedirect.com/science/article/pii/S2589004222008665

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