Clinico-psychopathological characteristics of patients with residual states in long-term schizophrenia

Introduction Long-term schizophrenia, even in remission, is necessarily accompanied by residual symptoms that may be quite pronounced and may significantly affect many aspects of the patient’s life, requiring exploration of specific therapeutic approaches. The alleviation of residual symptoms is an...

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Main Authors: V. Mitikhin, M. Kuzminova
Format: Article
Language:English
Published: Cambridge University Press 2023-03-01
Series:European Psychiatry
Online Access:https://www.cambridge.org/core/product/identifier/S0924933823023192/type/journal_article
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author V. Mitikhin
M. Kuzminova
author_facet V. Mitikhin
M. Kuzminova
author_sort V. Mitikhin
collection DOAJ
description Introduction Long-term schizophrenia, even in remission, is necessarily accompanied by residual symptoms that may be quite pronounced and may significantly affect many aspects of the patient’s life, requiring exploration of specific therapeutic approaches. The alleviation of residual symptoms is an important factor in the patient’s better adjustment. Objectives Assessment and study clinical characteristics long-term schizophrenia. Methods Clinical, statistical, psychometric. A total of 90 patients, mean age 66,6±13,3 years, 26 males, 64 females were examined. Results Negative symptoms were predominant in patients with long-term schizophrenia (17,8±6,7). It was represented by: abstract thinking disorders (2,8±1,0), stereotyped thinking (2,7±1,1), passive-apathetic social isolation (2,6±1,2), avolition (2,6±0,8), flattening of affect (2,5±0,8). It manifested as lack of expressiveness in facial expressions and gestures, deficit of communicative gestures as well as emotional indifference (2,4±1,1), limitation of contacts with people, and spontaneous and fluent speech impairments. Positive symptoms were rare, mainly represented by suspiciousness (2,2±1,2), sometimes rising to delirium (1,8±1,4). Conceptual disorganization was detected in 1,9±0,7. Agitation and aggression were generally not characteristic of those surveyed. Depression/anxiety was quite pronounced in patients with long-term schizophrenia. Depression (1,8±0,8) was represented by low mood, hopelessness and loss of social interests. Anxiety (2,9±1,2) was even more prominent and predominant amongst all symptoms. Conclusions The authors expanded our understanding of the clinical characteristics of residual symptoms of long-term schizophrenia to allow timely identification and provision of medical and rehabilitative care. Disclosure of Interest None Declared
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spelling doaj.art-db8f322669fa4f4faa2bfdbe624294e22023-11-17T05:07:19ZengCambridge University PressEuropean Psychiatry0924-93381778-35852023-03-0166S1092S109210.1192/j.eurpsy.2023.2319Clinico-psychopathological characteristics of patients with residual states in long-term schizophreniaV. Mitikhin0M. Kuzminova1Department of Mental Health Support Systems Research Centre, Mental Health Research Centre, Moscow, Russian FederationDepartment of Mental Health Support Systems Research Centre, Mental Health Research Centre, Moscow, Russian Federation Introduction Long-term schizophrenia, even in remission, is necessarily accompanied by residual symptoms that may be quite pronounced and may significantly affect many aspects of the patient’s life, requiring exploration of specific therapeutic approaches. The alleviation of residual symptoms is an important factor in the patient’s better adjustment. Objectives Assessment and study clinical characteristics long-term schizophrenia. Methods Clinical, statistical, psychometric. A total of 90 patients, mean age 66,6±13,3 years, 26 males, 64 females were examined. Results Negative symptoms were predominant in patients with long-term schizophrenia (17,8±6,7). It was represented by: abstract thinking disorders (2,8±1,0), stereotyped thinking (2,7±1,1), passive-apathetic social isolation (2,6±1,2), avolition (2,6±0,8), flattening of affect (2,5±0,8). It manifested as lack of expressiveness in facial expressions and gestures, deficit of communicative gestures as well as emotional indifference (2,4±1,1), limitation of contacts with people, and spontaneous and fluent speech impairments. Positive symptoms were rare, mainly represented by suspiciousness (2,2±1,2), sometimes rising to delirium (1,8±1,4). Conceptual disorganization was detected in 1,9±0,7. Agitation and aggression were generally not characteristic of those surveyed. Depression/anxiety was quite pronounced in patients with long-term schizophrenia. Depression (1,8±0,8) was represented by low mood, hopelessness and loss of social interests. Anxiety (2,9±1,2) was even more prominent and predominant amongst all symptoms. Conclusions The authors expanded our understanding of the clinical characteristics of residual symptoms of long-term schizophrenia to allow timely identification and provision of medical and rehabilitative care. Disclosure of Interest None Declaredhttps://www.cambridge.org/core/product/identifier/S0924933823023192/type/journal_article
spellingShingle V. Mitikhin
M. Kuzminova
Clinico-psychopathological characteristics of patients with residual states in long-term schizophrenia
European Psychiatry
title Clinico-psychopathological characteristics of patients with residual states in long-term schizophrenia
title_full Clinico-psychopathological characteristics of patients with residual states in long-term schizophrenia
title_fullStr Clinico-psychopathological characteristics of patients with residual states in long-term schizophrenia
title_full_unstemmed Clinico-psychopathological characteristics of patients with residual states in long-term schizophrenia
title_short Clinico-psychopathological characteristics of patients with residual states in long-term schizophrenia
title_sort clinico psychopathological characteristics of patients with residual states in long term schizophrenia
url https://www.cambridge.org/core/product/identifier/S0924933823023192/type/journal_article
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AT mkuzminova clinicopsychopathologicalcharacteristicsofpatientswithresidualstatesinlongtermschizophrenia