The benefits of clustering in TNF receptor superfamily signaling

The tumor necrosis factor (TNF) receptor superfamily is a structurally and functionally related group of cell surface receptors that play crucial roles in various cellular processes, including apoptosis, cell survival, and immune regulation. This review paper synthesizes key findings from recent stu...

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书目详细资料
Main Authors: Éva S. Vanamee, Denise L. Faustman
格式: 文件
语言:English
出版: Frontiers Media S.A. 2023-08-01
丛编:Frontiers in Immunology
主题:
在线阅读:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1225704/full
实物特征
总结:The tumor necrosis factor (TNF) receptor superfamily is a structurally and functionally related group of cell surface receptors that play crucial roles in various cellular processes, including apoptosis, cell survival, and immune regulation. This review paper synthesizes key findings from recent studies, highlighting the importance of clustering in TNF receptor superfamily signaling. We discuss the underlying molecular mechanisms of signaling, the functional consequences of receptor clustering, and potential therapeutic implications of targeting surface structures of receptor complexes.
ISSN:1664-3224