The benefits of clustering in TNF receptor superfamily signaling

The benefits of clustering in TNF receptor superfamily signaling

The tumor necrosis factor (TNF) receptor superfamily is a structurally and functionally related group of cell surface receptors that play crucial roles in various cellular processes, including apoptosis, cell survival, and immune regulation. This review paper synthesizes key findings from recent stu...

Descrición completa

Detalles Bibliográficos
Main Authors:	Éva S. Vanamee, Denise L. Faustman
Formato:	Artigo
Idioma:	English
Publicado:	Frontiers Media S.A. 2023-08-01
Series:	Frontiers in Immunology
Subjects:	TNF receptor superfamily (TNFRSF) TNF signaling receptor clustering TNFR agonism and antagonism signal amplification
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1225704/full

Títulos similares

Signal Amplification in Highly Ordered Networks Is Driven by Geometry
por: Éva S. Vanamee, et al.
Publicado: (2022-01-01)

Receptor Oligomerization and Its Relevance for Signaling by Receptors of the Tumor Necrosis Factor Receptor Superfamily
por: Kirstin Kucka, et al.
Publicado: (2021-02-01)

Editorial: TNFR Superfamily Oligomerization and Signaling
por: Olivier Micheau, et al.
Publicado: (2021-04-01)

TNF RECEPTOR 2 AND DISEASE: Autoimmunity and Regenerative Medicine
por: Denise Louise Faustman, et al.
Publicado: (2013-12-01)

Regulation of Tissue Responses: The TWEAK/Fn14 Pathway and other TNF/ TNFR Superfamily Members that Can Signal through noncanonical NFkB
por: Linda C Burkly
Publicado: (2015-03-01)

Reconciling intrinsic properties of activating TNF receptors by native ligands versus synthetic agonists
por: George Fromm, et al.
Publicado: (2023-09-01)

The Roles of TNF Signaling Pathways in Metabolism of Bone Tumors
por: Haiying Zhou, et al.
Publicado: (2022-06-01)

On the TRAIL of Better Therapies: Understanding TNFRSF Structure-Function
por: Éva S. Vanamee, et al.
Publicado: (2020-03-01)

TNF superfamily control of tissue remodeling and fibrosis
por: Hope Steele, et al.
Publicado: (2023-07-01)

Deletion of the non-adjacent genes UL148 and UL148D impairs human cytomegalovirus-mediated TNF receptor 2 surface upregulation
por: Vu Thuy Khanh Le-Trilling, et al.
Publicado: (2023-08-01)

Receptor Specificity Engineering of TNF Superfamily Ligands
por: Fengzhi Suo, et al.
Publicado: (2022-01-01)

Characterization of B- and T-Cell Compartment and B-Cell Related Factors Belonging to the TNF/TNFR Superfamily in Patients With Clinically Active Systemic Lupus Erythematosus: Baseline BAFF Serum Levels Are the Strongest Predictor of Response to Belimumab after Twelve Months of Therapy
por: Silvia Piantoni, et al.
Publicado: (2021-05-01)

The role of the TNF receptors and apoptosis inducing ligands in tumor growth
por: O. H. Minchenko1, et al.
Publicado: (2016-10-01)

Susceptibility to pulmonary tuberculosis: host genetic deficiency in tumor necrosis factor alpha (TNF-α) gene and tumor necrosis factor receptor 2 (TNFR2)
por: Ehsan Ghamari, et al.
Publicado: (2016-01-01)

TNFR1 Absence Is Not Crucial for Different Types of Cell Reaction to TNF: A Study of the TNFR1-Knockout Cell Model
por: Alina A. Alshevskaya, et al.
Publicado: (2024-04-01)

Tumor necrosis factor superfamily in multiple sclerosis: from pathology to therapeutic implications
por: Federica Azzolini, et al.
Publicado: (2023-05-01)

Preclinical and clinical aspects of TNF-α and its receptors TNFR1 and TNFR2 in breast cancer
por: Isela Martínez-Reza, et al.
Publicado: (2017-12-01)

Selective Targeting of TNF Receptors as a Novel Therapeutic Approach
por: Roman Fischer, et al.
Publicado: (2020-05-01)

Therapeutic potential of TNFα inhibitors in chronic inflammatory disorders: Past and future
por: Hongtao Zhang, et al.
Publicado: (2021-01-01)

Bilateral muscle fiber and nerve influences by TNF-alpha in response to unilateral muscle overuse – studies on TNF receptor expressions
por: Lina Renström, et al.
Publicado: (2017-11-01)

Generation and characterization of OX40-ligand fusion protein that agonizes OX40 on T-Lymphocytes
por: Ayaka Sato, et al.
Publicado: (2025-01-01)

TRAF1 Signaling in Human Health and Disease
por: Maria I. Edilova, et al.
Publicado: (2018-12-01)

A patch of positively charged residues regulates the efficacy of clinical DR5 antibodies in solid tumors
por: Gururaj Shivange, et al.
Publicado: (2021-11-01)

Extracellular Vesicles from Hyperammonemic Rats Induce Neuroinflammation and Motor Incoordination in Control Rats
por: Paula Izquierdo-Altarejos, et al.
Publicado: (2020-02-01)

Co-expression of TNF receptors 1 and 2 on melanomas facilitates soluble TNF-induced resistance to MAPK pathway inhibitors
por: Cindy A. Sander, et al.
Publicado: (2022-07-01)

Super-Resolution Imaging of Fas/CD95 Reorganization Induced by Membrane-Bound Fas Ligand Reveals Nanoscale Clustering Upstream of FADD Recruitment
por: Nicholas Frazzette, et al.
Publicado: (2022-06-01)

Tumor Necrosis Factor Receptors: Pleiotropic Signaling Complexes and Their Differential Effects
por: Portia Gough, et al.
Publicado: (2020-11-01)

Targeting of Tumor Necrosis Factor Alpha Receptors as a Therapeutic Strategy for Neurodegenerative Disorders
por: Yun Dong, et al.
Publicado: (2015-11-01)

Re-Examining the Role of TNF in MS Pathogenesis and Therapy
por: Diego Fresegna, et al.
Publicado: (2020-10-01)

Leveraging the tolerogenic potential of TNF-α and regulatory B cells in organ transplantation
por: Sonya A. Poznansky, et al.
Publicado: (2023-04-01)

Novel anti-atrophic peptide isolated from olive flounder surimi as a nutraceutical additive against TNF-α induced muscle atrophy
por: N.M. Liyanage, et al.
Publicado: (2023-11-01)

Immunosuppressant Therapies in COVID-19: Is the TNF Axis an Alternative?
por: Yadira Palacios, et al.
Publicado: (2022-05-01)

Modulation of Regulatory T Cell Activity by TNF Receptor Type II-Targeting Pharmacological Agents
por: Huimin Zou, et al.
Publicado: (2018-03-01)

Reverse Signaling Contributes to Control of Chronic Inflammation by Anti-TNF Therapeutics
por: Orsolya Sipos, et al.
Publicado: (2015-06-01)

Association of TNFRSF19 with a TNF family-based prognostic model and subtypes in gliomas using machine learning
por: Youwei Guo, et al.
Publicado: (2024-04-01)

Anti-TNF-α Compounds as a Treatment for Depression
por: Sarit Uzzan, et al.
Publicado: (2021-04-01)

Concomitant Retinal Alterations in Neuronal Activity and TNFα Pathway Are Detectable during the Pre-Symptomatic Stage in a Mouse Model of Alzheimer’s Disease
por: Virginie Dinet, et al.
Publicado: (2022-05-01)

Consequences of the Lack of TNFR1 in Ouabain Response in the Hippocampus of C57BL/6J Mice
por: Paula Fernanda Kinoshita, et al.
Publicado: (2022-11-01)

The evolution of TNF signaling in platyhelminths suggests the cooptation of TNF receptor in the host-parasite interplay
por: Claudio R. Bertevello, et al.
Publicado: (2020-09-01)

Eosinophil recruitment in TNF-receptor-deficient mice
por: Shepherd Malcolm, et al.
Publicado: (2001-06-01)