Forebrain overexpression of CaMKII abolishes cingulate long term depression and reduces mechanical allodynia and thermal hyperalgesia

Forebrain overexpression of CaMKII abolishes cingulate long term depression and reduces mechanical allodynia and thermal hyperalgesia

<p>Abstract</p> <p>Activity-dependent synaptic plasticity is known to be important in learning and memory, persistent pain and drug addiction. Glutamate NMDA receptor activation stimulates several protein kinases, which then trigger biochemical cascades that lead to modifications i...

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Bibliographic Details
Main Authors: Tsien Joe Z, Wang Huimin, Shokat Kevan M, Zhang Chao, Wang Guo-Du, Wei Feng, Liauw Jason, Zhuo Min
Format: Article
Language:English
Published: SAGE Publishing 2006-06-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/2/1/21

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