Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness

Oligomerisation of transcription factors regulates their translocation into the nucleus, DNA binding affinity and sequence specificity. Here, Hinde et al. present a microscopy analysis, pair correlation of molecular brightness, that tracks the molecular mobility of different oligomeric species in th...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Elizabeth Hinde, Elvis Pandžić, Zhengmin Yang, Ivan H. W. Ng, David A. Jans, Marie A. Bogoyevitch, Enrico Gratton, Katharina Gaus
Format: Artikel
Sprache:English
Veröffentlicht: Nature Portfolio 2016-03-01
Schriftenreihe:Nature Communications
Online Zugang:https://doi.org/10.1038/ncomms11047