Markers of subclinical atherosclerosis in the ten-year risk estimation of cardiovascular events
The information content of SCORE model in the evaluation of the total ten-year cardiovascular risk in an isolated sample of 207 males without clinical manifestations of atherosclerosis was investigated. It was revealed that the most of the observations from persons who had attained over a 10-year pe...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Concilium Medicum
2015-12-01
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| Series: | КардиоСоматика |
| Subjects: | |
| Online Access: | https://cardiosomatics.orscience.ru/2221-7185/article/view/45158 |
| _version_ | 1818926948622008320 |
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| author | P. V Bovtyushko S. L Grishaev A. Ye Filippov A. G Obrezan |
| author_facet | P. V Bovtyushko S. L Grishaev A. Ye Filippov A. G Obrezan |
| author_sort | P. V Bovtyushko |
| collection | DOAJ |
| description | The information content of SCORE model in the evaluation of the total ten-year cardiovascular risk in an isolated sample of 207 males without clinical manifestations of atherosclerosis was investigated. It was revealed that the most of the observations from persons who had attained over a 10-year period of the combined end point, the model qualified incorrectly, which didn’t meet the requirements of individual risk assessment in a limited sample group of males. It is shown that the inclusion of subclinical atherosclerosis markers in SCORE model can significantly improve its sensitivity. At the same time, a group of poor prognosis gets a significant number of observations for individuals free of cardiovascular events due to the high probability of false positive response. |
| first_indexed | 2024-12-20T03:05:14Z |
| format | Article |
| id | doaj.art-db99da5c85144f4798ed1f0289c60aaa |
| institution | Directory Open Access Journal |
| issn | 2221-7185 2658-5707 |
| language | English |
| last_indexed | 2024-12-20T03:05:14Z |
| publishDate | 2015-12-01 |
| publisher | Concilium Medicum |
| record_format | Article |
| series | КардиоСоматика |
| spelling | doaj.art-db99da5c85144f4798ed1f0289c60aaa2022-12-21T19:55:37ZengConcilium MedicumКардиоСоматика2221-71852658-57072015-12-0164121640824Markers of subclinical atherosclerosis in the ten-year risk estimation of cardiovascular eventsP. V Bovtyushko0S. L Grishaev1A. Ye Filippov2A. G Obrezan3Medico-military academy named after KirovMedico-military academy named after KirovSaint-Petersburg State UniversitySaint-Petersburg State UniversityThe information content of SCORE model in the evaluation of the total ten-year cardiovascular risk in an isolated sample of 207 males without clinical manifestations of atherosclerosis was investigated. It was revealed that the most of the observations from persons who had attained over a 10-year period of the combined end point, the model qualified incorrectly, which didn’t meet the requirements of individual risk assessment in a limited sample group of males. It is shown that the inclusion of subclinical atherosclerosis markers in SCORE model can significantly improve its sensitivity. At the same time, a group of poor prognosis gets a significant number of observations for individuals free of cardiovascular events due to the high probability of false positive response.https://cardiosomatics.orscience.ru/2221-7185/article/view/45158atherosclerosiscardiovascular eventscombined endpointscore modelatheromaarterial intima- media thickness |
| spellingShingle | P. V Bovtyushko S. L Grishaev A. Ye Filippov A. G Obrezan Markers of subclinical atherosclerosis in the ten-year risk estimation of cardiovascular events КардиоСоматика atherosclerosis cardiovascular events combined endpoint score model atheroma arterial intima- media thickness |
| title | Markers of subclinical atherosclerosis in the ten-year risk estimation of cardiovascular events |
| title_full | Markers of subclinical atherosclerosis in the ten-year risk estimation of cardiovascular events |
| title_fullStr | Markers of subclinical atherosclerosis in the ten-year risk estimation of cardiovascular events |
| title_full_unstemmed | Markers of subclinical atherosclerosis in the ten-year risk estimation of cardiovascular events |
| title_short | Markers of subclinical atherosclerosis in the ten-year risk estimation of cardiovascular events |
| title_sort | markers of subclinical atherosclerosis in the ten year risk estimation of cardiovascular events |
| topic | atherosclerosis cardiovascular events combined endpoint score model atheroma arterial intima- media thickness |
| url | https://cardiosomatics.orscience.ru/2221-7185/article/view/45158 |
| work_keys_str_mv | AT pvbovtyushko markersofsubclinicalatherosclerosisinthetenyearriskestimationofcardiovascularevents AT slgrishaev markersofsubclinicalatherosclerosisinthetenyearriskestimationofcardiovascularevents AT ayefilippov markersofsubclinicalatherosclerosisinthetenyearriskestimationofcardiovascularevents AT agobrezan markersofsubclinicalatherosclerosisinthetenyearriskestimationofcardiovascularevents |