Comparison of immunological characteristics between paired mismatch repair-proficient and -deficient colorectal cancer patients

Comparison of immunological characteristics between paired mismatch repair-proficient and -deficient colorectal cancer patients

Abstract Background Currently, mismatch repair-deficient (dMMR) status is a promising candidate for targeted immune checkpoint inhibition therapy in colorectal cancer (CRC) patients, however, the potential immunological mechanism has not yet been well clarified and some other predictors need to be e...

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Bibliographic Details
Main Authors: Shou-Sheng Liu, Yuan-Zhong Yang, Chang Jiang, Qi Quan, Qian-Kun Xie, Xiao-Pai Wang, Wen-Zhuo He, Yu-Ming Rong, Ping Chen, Qiong Yang, Lin Yang, Bei Zhang, Xiao-Jun Xia, Peng-Fei Kong, Liang-Ping Xia
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Journal of Translational Medicine
Subjects:
Colorectal cancer
Mismatch repair-deficient
Mismatch repair-proficient
MHC class I molecules
Programmed death-1
Online Access:http://link.springer.com/article/10.1186/s12967-018-1570-z

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http://link.springer.com/article/10.1186/s12967-018-1570-z

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