Indicators of cell and humoral immune response under pulmonary tuberculosis accompanied by eosinophilia

The data of the comparative analysis of separate parameters of cell and humoral chains of immune response in patients suffering from pulmonary tuberculosis accompanied by eosinophilia has been presented in the article.With involving contemporary immunological methods of research, it has been stated...

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Main Authors: Yu. V. Kolobovnikova, O. I. Urazova, V. V. Novitsky, O. V Voronkova, K. O. Mikheyeva, M. V. Ignatov, O. V. Filinyuk, O. I. Novoseltseva, Ye. P. Stepanova
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2012-02-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/405
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author Yu. V. Kolobovnikova
O. I. Urazova
V. V. Novitsky
O. V Voronkova
K. O. Mikheyeva
M. V. Ignatov
O. V. Filinyuk
O. I. Novoseltseva
Ye. P. Stepanova
author_facet Yu. V. Kolobovnikova
O. I. Urazova
V. V. Novitsky
O. V Voronkova
K. O. Mikheyeva
M. V. Ignatov
O. V. Filinyuk
O. I. Novoseltseva
Ye. P. Stepanova
author_sort Yu. V. Kolobovnikova
collection DOAJ
description The data of the comparative analysis of separate parameters of cell and humoral chains of immune response in patients suffering from pulmonary tuberculosis accompanied by eosinophilia has been presented in the article.With involving contemporary immunological methods of research, it has been stated that tuberculosis infection in combination with eosinophilic blood reaction is accompanied by marked cytokine imbalance, characterized by increase in the concentration of IL-5 (mediator with anti-inflammatory activity) in blood serum against the background of low serum level of the key anti-tuberculosis cytokine — IFN-γ.
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spelling doaj.art-db9e06d7bc2d4ca3bd49b12bbb04f8192023-03-13T09:58:16ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842012-02-01111394510.20538/1682-0363-2012-1-39-45383Indicators of cell and humoral immune response under pulmonary tuberculosis accompanied by eosinophiliaYu. V. Kolobovnikova0O. I. Urazova1V. V. Novitsky2O. V Voronkova3K. O. Mikheyeva4M. V. Ignatov5O. V. Filinyuk6O. I. Novoseltseva7Ye. P. Stepanova8Сибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскОГУЗ «Областная туберкулезная клиническая больница», г. ТомскОГУЗ «Областная туберкулезная клиническая больница», г. ТомскThe data of the comparative analysis of separate parameters of cell and humoral chains of immune response in patients suffering from pulmonary tuberculosis accompanied by eosinophilia has been presented in the article.With involving contemporary immunological methods of research, it has been stated that tuberculosis infection in combination with eosinophilic blood reaction is accompanied by marked cytokine imbalance, characterized by increase in the concentration of IL-5 (mediator with anti-inflammatory activity) in blood serum against the background of low serum level of the key anti-tuberculosis cytokine — IFN-γ.https://bulletin.ssmu.ru/jour/article/view/405туберкулез легкихэозинофилылимфоцитыцитокины
spellingShingle Yu. V. Kolobovnikova
O. I. Urazova
V. V. Novitsky
O. V Voronkova
K. O. Mikheyeva
M. V. Ignatov
O. V. Filinyuk
O. I. Novoseltseva
Ye. P. Stepanova
Indicators of cell and humoral immune response under pulmonary tuberculosis accompanied by eosinophilia
Бюллетень сибирской медицины
туберкулез легких
эозинофилы
лимфоциты
цитокины
title Indicators of cell and humoral immune response under pulmonary tuberculosis accompanied by eosinophilia
title_full Indicators of cell and humoral immune response under pulmonary tuberculosis accompanied by eosinophilia
title_fullStr Indicators of cell and humoral immune response under pulmonary tuberculosis accompanied by eosinophilia
title_full_unstemmed Indicators of cell and humoral immune response under pulmonary tuberculosis accompanied by eosinophilia
title_short Indicators of cell and humoral immune response under pulmonary tuberculosis accompanied by eosinophilia
title_sort indicators of cell and humoral immune response under pulmonary tuberculosis accompanied by eosinophilia
topic туберкулез легких
эозинофилы
лимфоциты
цитокины
url https://bulletin.ssmu.ru/jour/article/view/405
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