<i>Quercus acuta</i> Thunb. (Fagaceae) and Its Component, Isoquercitrin, Inhibit HSV-1 Replication by Suppressing Virus-Induced ROS Production and NF-κB Activation

<i>Quercus acuta</i> Thunb. (Fagaceae) and Its Component, Isoquercitrin, Inhibit HSV-1 Replication by Suppressing Virus-Induced ROS Production and NF-κB Activation

HSV-1 is a neurotropic virus that replicates lytically during acute infection and establishes latency in peripheral neurons. Currently, the clinically approved compounds for the prevention of HSV-1 infection include acyclovir and penciclovir; however, long-term use of the drug is associated with ser...

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Bibliographic Details
Main Authors: Buyun Kim, Young Soo Kim, Youn-Hwan Hwang, Hye Jin Yang, Wei Li, Eun-Bin Kwon, Tae In Kim, Younghoon Go, Jang-Gi Choi
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Antioxidants
Subjects:
HSV-1
<i>Quercus acuta</i> Thunb.
isoquercitrin
ROS
NF-κB
ICP27
Online Access:https://www.mdpi.com/2076-3921/10/10/1638

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