Experimental Detection and Simulation of Terahertz Spectra of Aqueous L-Arginine
Terahertz (THz) wave is a good candidate for biological sample detection, because vibration and rotation energy levels of biomolecule are in THz band. However, the strong absorption of THz wave by water in biological samples hinders its development. In this paper, a method for direct detection of TH...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Biosensors |
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| Online Access: | https://www.mdpi.com/2079-6374/12/11/1029 |
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| author | Lei Hou Junnan Wang Haiqing Wang Lei Yang Wei Shi |
| author_facet | Lei Hou Junnan Wang Haiqing Wang Lei Yang Wei Shi |
| author_sort | Lei Hou |
| collection | DOAJ |
| description | Terahertz (THz) wave is a good candidate for biological sample detection, because vibration and rotation energy levels of biomolecule are in THz band. However, the strong absorption of THz wave by water in biological samples hinders its development. In this paper, a method for direct detection of THz absorption spectra of L-arginine suspension was proposed by using a strong field THz radiation source combined with a polyethylene cell with micrometer thickness in a THz time-domain spectroscopy system. And the THz absorption spectrum of L-arginine solution was simulated by the density functional theory and the simulation result is in good agreement with the experimental results. Finally, the types of chemical bond interaction that cause the absorption peak are identified based on the experimental and simulation results. This work paves a way to investigate the THz absorption spectra and intramolecular interactions of aqueous biological samples. |
| first_indexed | 2024-03-09T18:27:50Z |
| format | Article |
| id | doaj.art-dba08544b69d4ecc91495df94fb9f60a |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-09T18:27:50Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-dba08544b69d4ecc91495df94fb9f60a2023-11-24T07:48:48ZengMDPI AGBiosensors2079-63742022-11-011211102910.3390/bios12111029Experimental Detection and Simulation of Terahertz Spectra of Aqueous L-ArginineLei Hou0Junnan Wang1Haiqing Wang2Lei Yang3Wei Shi4Department of Physics, Xi’an University of Technology, Xi’an 710048, ChinaSchool of Electrical Engineering, Xi’an University of Technology, Xi’an 710048, ChinaDepartment of Physics, Xi’an University of Technology, Xi’an 710048, ChinaSchool of Electrical Engineering, Xi’an University of Technology, Xi’an 710048, ChinaDepartment of Physics, Xi’an University of Technology, Xi’an 710048, ChinaTerahertz (THz) wave is a good candidate for biological sample detection, because vibration and rotation energy levels of biomolecule are in THz band. However, the strong absorption of THz wave by water in biological samples hinders its development. In this paper, a method for direct detection of THz absorption spectra of L-arginine suspension was proposed by using a strong field THz radiation source combined with a polyethylene cell with micrometer thickness in a THz time-domain spectroscopy system. And the THz absorption spectrum of L-arginine solution was simulated by the density functional theory and the simulation result is in good agreement with the experimental results. Finally, the types of chemical bond interaction that cause the absorption peak are identified based on the experimental and simulation results. This work paves a way to investigate the THz absorption spectra and intramolecular interactions of aqueous biological samples.https://www.mdpi.com/2079-6374/12/11/1029terahertz wavesL-arginineterahertz time-domain spectroscopy systemdensity functional theoryinteraction region indicator |
| spellingShingle | Lei Hou Junnan Wang Haiqing Wang Lei Yang Wei Shi Experimental Detection and Simulation of Terahertz Spectra of Aqueous L-Arginine Biosensors terahertz waves L-arginine terahertz time-domain spectroscopy system density functional theory interaction region indicator |
| title | Experimental Detection and Simulation of Terahertz Spectra of Aqueous L-Arginine |
| title_full | Experimental Detection and Simulation of Terahertz Spectra of Aqueous L-Arginine |
| title_fullStr | Experimental Detection and Simulation of Terahertz Spectra of Aqueous L-Arginine |
| title_full_unstemmed | Experimental Detection and Simulation of Terahertz Spectra of Aqueous L-Arginine |
| title_short | Experimental Detection and Simulation of Terahertz Spectra of Aqueous L-Arginine |
| title_sort | experimental detection and simulation of terahertz spectra of aqueous l arginine |
| topic | terahertz waves L-arginine terahertz time-domain spectroscopy system density functional theory interaction region indicator |
| url | https://www.mdpi.com/2079-6374/12/11/1029 |
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