Specific-cytokine associations with outcomes in knee osteoarthritis subgroups: breaking down disease heterogeneity with phenotyping

Specific-cytokine associations with outcomes in knee osteoarthritis subgroups: breaking down disease heterogeneity with phenotyping

Abstract Background Despite existing extensive literature, a comprehensive and clinically relevant classification system for osteoarthritis (OA) has yet to be established. In this study, we aimed to further characterize four knee OA (KOA) inflammatory phenotypes (KOIP) recently proposed by our group...

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Main Authors: Joan Calvet, Antoni Berenguer-Llergo, Cristóbal Orellana, María García-Manrique, Menna Rusiñol, Silvia Garcia-Cirera, Maria Llop, Marta Arévalo, Alba Garcia-Pinilla, Carlos Galisteo, Cristina Aymerich, Rafael Gómez, Alejandra Serrano, Anna Carreras, Jordi Gratacós
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Arthritis Research & Therapy
Subjects:
Knee osteoarthritis
Cytokines
Phenotype
Inflammation
Clinical severity
Radiographic progression
Online Access:https://doi.org/10.1186/s13075-023-03244-y

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