Colorectal Polyps: A Histopathological Study in Tertiary Care Center
Introduction: Gastrointestinal polyps are commonly encountered in the colorectal region. They can be non-neoplastic or neoplastic. Neoplastic polyps include adenomas which are clinically important because of their premalignant nature. The study was carried out to analyze the histomorphological spect...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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HEAD Nepal
2021-06-01
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| Series: | Nepalese Medical Journal |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/nmj/article/view/37707 |
| _version_ | 1819080014259290112 |
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| author | Dipika Basnet Ramesh Makaju Ram Bahadur Gurung Rachana Dhakal |
| author_facet | Dipika Basnet Ramesh Makaju Ram Bahadur Gurung Rachana Dhakal |
| author_sort | Dipika Basnet |
| collection | DOAJ |
| description | Introduction: Gastrointestinal polyps are commonly encountered in the colorectal region. They can be non-neoplastic or neoplastic. Neoplastic polyps include adenomas which are clinically important because of their premalignant nature. The study was carried out to analyze the histomorphological spectrum of polyps; in our institution with special emphasis on adenomatous polyps.
Material and methods: This is a retrospective study done from January 2015 to December 2019 in the Department of Pathology, Dhulikhel Hospital - Kathmandu University Hospital (DH - KUH). Relevant clinical data of the patients were obtained from the histopathological records of the patient from the pathology department and biopsies stained with Haematoxylin and Eosin were studied under the light microscope.
Results: A total of 168 cases of polyp were studied from 125 patients. The most common indication for colonoscopy in patients with polyp was per rectal bleeding. The age of the patient ranged from 2 to 83 years. The rectum was the commonest location. 106(63.1%) of polyps were non-neoplastic and 6(36.9%) of polyps were neoplastic. Juvenile polyp(71;42.3%) was the commonest polyp. Tubular adenoma(55;32.7%) was the commonest neoplastic polyp. The
maximum number of neoplastic polyps were seen in the age group of 51-60years (11;29.7%). Male predominance was seen in neoplastic as well as a non-neoplastic polyp. High grade adenoma(4;6.7%) was more commonly seen in adenomatous polyp >2cm(3;75%) followed by 1-2cm(1;25%) and none in <1cm.
Conclusions: This study gives a fair insight into the distribution of neoplastic and nonneoplastic polyp in the colorectal region. Adenomatous polyps are premalignant. |
| first_indexed | 2024-12-21T19:38:09Z |
| format | Article |
| id | doaj.art-dba37623c0d042e18d3abfa12f0efc6e |
| institution | Directory Open Access Journal |
| issn | 2631-2093 2645-8586 |
| language | English |
| last_indexed | 2024-12-21T19:38:09Z |
| publishDate | 2021-06-01 |
| publisher | HEAD Nepal |
| record_format | Article |
| series | Nepalese Medical Journal |
| spelling | doaj.art-dba37623c0d042e18d3abfa12f0efc6e2022-12-21T18:52:33ZengHEAD NepalNepalese Medical Journal2631-20932645-85862021-06-014141441810.3126/nmj.v4i1.3770734494Colorectal Polyps: A Histopathological Study in Tertiary Care CenterDipika Basnet0https://orcid.org/0000-0002-5103-9445Ramesh Makaju1Ram Bahadur Gurung2Rachana Dhakal3https://orcid.org/0000-0003-2189-8369Dhulikhel hospital, Kathmandu university hospital, dhulikhel, NepalKathmandu University School of Medical SciencesKathmandu University School of Medical SciencesKathmandu University School of Medical SciencesIntroduction: Gastrointestinal polyps are commonly encountered in the colorectal region. They can be non-neoplastic or neoplastic. Neoplastic polyps include adenomas which are clinically important because of their premalignant nature. The study was carried out to analyze the histomorphological spectrum of polyps; in our institution with special emphasis on adenomatous polyps. Material and methods: This is a retrospective study done from January 2015 to December 2019 in the Department of Pathology, Dhulikhel Hospital - Kathmandu University Hospital (DH - KUH). Relevant clinical data of the patients were obtained from the histopathological records of the patient from the pathology department and biopsies stained with Haematoxylin and Eosin were studied under the light microscope. Results: A total of 168 cases of polyp were studied from 125 patients. The most common indication for colonoscopy in patients with polyp was per rectal bleeding. The age of the patient ranged from 2 to 83 years. The rectum was the commonest location. 106(63.1%) of polyps were non-neoplastic and 6(36.9%) of polyps were neoplastic. Juvenile polyp(71;42.3%) was the commonest polyp. Tubular adenoma(55;32.7%) was the commonest neoplastic polyp. The maximum number of neoplastic polyps were seen in the age group of 51-60years (11;29.7%). Male predominance was seen in neoplastic as well as a non-neoplastic polyp. High grade adenoma(4;6.7%) was more commonly seen in adenomatous polyp >2cm(3;75%) followed by 1-2cm(1;25%) and none in <1cm. Conclusions: This study gives a fair insight into the distribution of neoplastic and nonneoplastic polyp in the colorectal region. Adenomatous polyps are premalignant.https://www.nepjol.info/index.php/nmj/article/view/37707adenoma; colorectal polyp; juvenile polyp |
| spellingShingle | Dipika Basnet Ramesh Makaju Ram Bahadur Gurung Rachana Dhakal Colorectal Polyps: A Histopathological Study in Tertiary Care Center Nepalese Medical Journal adenoma; colorectal polyp; juvenile polyp |
| title | Colorectal Polyps: A Histopathological Study in Tertiary Care Center |
| title_full | Colorectal Polyps: A Histopathological Study in Tertiary Care Center |
| title_fullStr | Colorectal Polyps: A Histopathological Study in Tertiary Care Center |
| title_full_unstemmed | Colorectal Polyps: A Histopathological Study in Tertiary Care Center |
| title_short | Colorectal Polyps: A Histopathological Study in Tertiary Care Center |
| title_sort | colorectal polyps a histopathological study in tertiary care center |
| topic | adenoma; colorectal polyp; juvenile polyp |
| url | https://www.nepjol.info/index.php/nmj/article/view/37707 |
| work_keys_str_mv | AT dipikabasnet colorectalpolypsahistopathologicalstudyintertiarycarecenter AT rameshmakaju colorectalpolypsahistopathologicalstudyintertiarycarecenter AT rambahadurgurung colorectalpolypsahistopathologicalstudyintertiarycarecenter AT rachanadhakal colorectalpolypsahistopathologicalstudyintertiarycarecenter |