Immunotherapies and immunomodulatory approaches in clinical trials - a mini review
The coronavirus disease (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created havoc worldwide. Due to the non-availability of any vaccine or drugs against COVID-19, immunotherapies involving convalescent plasma, immunoglobulins, antibodies (monocl...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-07-01
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| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2020.1871295 |
| _version_ | 1797677243922644992 |
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| author | Mohd. Iqbal Yatoo Zeenat Hamid Izhar Rather Qurat Ul Ain Nazir Riyaz Ahmed Bhat Abrar Ul Haq Suhail Nabi Magray Zulfqar Haq Ranjit Sah Ruchi Tiwari SenthilKumar Natesan Muhammad Bilal Harapan Harapan Kuldeep Dhama |
| author_facet | Mohd. Iqbal Yatoo Zeenat Hamid Izhar Rather Qurat Ul Ain Nazir Riyaz Ahmed Bhat Abrar Ul Haq Suhail Nabi Magray Zulfqar Haq Ranjit Sah Ruchi Tiwari SenthilKumar Natesan Muhammad Bilal Harapan Harapan Kuldeep Dhama |
| author_sort | Mohd. Iqbal Yatoo |
| collection | DOAJ |
| description | The coronavirus disease (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created havoc worldwide. Due to the non-availability of any vaccine or drugs against COVID-19, immunotherapies involving convalescent plasma, immunoglobulins, antibodies (monoclonal or polyclonal), and the use of immunomodulatory agents to enhance immunity are valuable alternative options. Cell-based therapies including natural killer cells, T cells, stem cells along with cytokines and toll-like receptors (TLRs) based therapies are also being exploited potentially against COVID-19. Future research need to strengthen the field of developing effective immunotherapeutics and immunomodulators with a thrust of providing appropriate, affordable, convenient, and cost-effective prophylactic and treatment regimens to combat global COVID-19 crisis that has led to a state of medical emergency enforcing entire countries of the world to devote their research infrastructure and manpower in tackling this pandemic. |
| first_indexed | 2024-03-11T22:42:14Z |
| format | Article |
| id | doaj.art-dba6e17a43404d38ac12064a01907184 |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T22:42:14Z |
| publishDate | 2021-07-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-dba6e17a43404d38ac12064a019071842023-09-22T08:51:53ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2021-07-011771897190910.1080/21645515.2020.18712951871295Immunotherapies and immunomodulatory approaches in clinical trials - a mini reviewMohd. Iqbal Yatoo0Zeenat Hamid1Izhar Rather2Qurat Ul Ain Nazir3Riyaz Ahmed Bhat4Abrar Ul Haq5Suhail Nabi Magray6Zulfqar Haq7Ranjit Sah8Ruchi Tiwari9SenthilKumar Natesan10Muhammad Bilal11Harapan Harapan12Kuldeep Dhama13Sher-E-Kashmir University of Agricultural Sciences and Technology of KashmirUniversity of KashmirSher-E-Kashmir University of Agricultural Sciences and Technology of KashmirSher-E-Kashmir University of Agricultural Sciences and Technology of KashmirSher-E-Kashmir University of Agricultural Sciences and Technology of KashmirSher-E-Kashmir University of Agricultural Sciences and Technology of KashmirSher-E-Kashmir University of Agricultural Sciences and Technology of KashmirSher-E-Kashmir University of Agricultural Sciences and Technology of KashmirTribhuvan University Teaching Hospital, Institute of MedicineCollege of Veterinary Sciences, UP Pandit Deen Dayal Upadhayay Pashu Chikitsa Vigyan Vishwavidyalay Evum Go-Anusandhan Sansthan (DUVASU)Indian Institute of Public Health GandhinagarHuaiyin Institute of TechnologyUniversitas Syiah KualaICAR-Indian Veterinary Research InstituteThe coronavirus disease (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created havoc worldwide. Due to the non-availability of any vaccine or drugs against COVID-19, immunotherapies involving convalescent plasma, immunoglobulins, antibodies (monoclonal or polyclonal), and the use of immunomodulatory agents to enhance immunity are valuable alternative options. Cell-based therapies including natural killer cells, T cells, stem cells along with cytokines and toll-like receptors (TLRs) based therapies are also being exploited potentially against COVID-19. Future research need to strengthen the field of developing effective immunotherapeutics and immunomodulators with a thrust of providing appropriate, affordable, convenient, and cost-effective prophylactic and treatment regimens to combat global COVID-19 crisis that has led to a state of medical emergency enforcing entire countries of the world to devote their research infrastructure and manpower in tackling this pandemic.http://dx.doi.org/10.1080/21645515.2020.1871295sars-cov-2covid-19immunotherapiesimmunomodulators |
| spellingShingle | Mohd. Iqbal Yatoo Zeenat Hamid Izhar Rather Qurat Ul Ain Nazir Riyaz Ahmed Bhat Abrar Ul Haq Suhail Nabi Magray Zulfqar Haq Ranjit Sah Ruchi Tiwari SenthilKumar Natesan Muhammad Bilal Harapan Harapan Kuldeep Dhama Immunotherapies and immunomodulatory approaches in clinical trials - a mini review Human Vaccines & Immunotherapeutics sars-cov-2 covid-19 immunotherapies immunomodulators |
| title | Immunotherapies and immunomodulatory approaches in clinical trials - a mini review |
| title_full | Immunotherapies and immunomodulatory approaches in clinical trials - a mini review |
| title_fullStr | Immunotherapies and immunomodulatory approaches in clinical trials - a mini review |
| title_full_unstemmed | Immunotherapies and immunomodulatory approaches in clinical trials - a mini review |
| title_short | Immunotherapies and immunomodulatory approaches in clinical trials - a mini review |
| title_sort | immunotherapies and immunomodulatory approaches in clinical trials a mini review |
| topic | sars-cov-2 covid-19 immunotherapies immunomodulators |
| url | http://dx.doi.org/10.1080/21645515.2020.1871295 |
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