Urinary exosomes from patients with diabetic kidney disease induced podocyte apoptosis via microRNA-145-5p/Srgap2 and the RhoA/ROCK pathway

Urinary exosomes from patients with diabetic kidney disease induced podocyte apoptosis via microRNA-145-5p/Srgap2 and the RhoA/ROCK pathway

Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease without early diagnostic and specific therapeutic approaches. Podocyte apoptosis and loss play important roles in the pathological process of DKD. This study aimed to explore whether urinary exosomes from type 2 diabetes pat...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Lulu Han, Shenghai Wang, Juan Li, Lulu Zhao, Hong Zhou
Format:	Artikel
Sprache:	English
Veröffentlicht:	Elsevier 2023-12-01
Schriftenreihe:	Experimental and Molecular Pathology
Schlagworte:	Diabetic kidney disease Urinary exosomes MicroRNA-145-5p Srgap2 ROCK Podocyte apoptosis
Online Zugang:	http://www.sciencedirect.com/science/article/pii/S001448002300028X

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