Inferior Vena Cava Oxygen Saturation during the First Three Postnatal Days in Preterm Newborns with and without Patent Ductus Arteriosus
Background: Inferior vena cava (IVC) oxygen saturation as an indicator of mixed venous oxygenation may be valuable for understanding postnatal adaptations in newborn infants. It is unknown how this parameter progresses in critically ill premature infants. Aims: To investigate IVC oxygen saturatio...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2014-09-01
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| Series: | Balkan Medical Journal |
| Subjects: | |
| Online Access: | http://balkanmedicaljournal.org/text.php?lang=en&id=290 |
| _version_ | 1828031160478859264 |
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| author | Ece Yapakçı Ayşe Ecevit Deniz Anuk İnce Hande Gülcan Aylin Tarcan Mahmut Gökdemir M. Agah Tekindal |
| author_facet | Ece Yapakçı Ayşe Ecevit Deniz Anuk İnce Hande Gülcan Aylin Tarcan Mahmut Gökdemir M. Agah Tekindal |
| author_sort | Ece Yapakçı |
| collection | DOAJ |
| description | Background: Inferior vena cava (IVC) oxygen saturation as an indicator of mixed venous oxygenation may be valuable for understanding postnatal adaptations in newborn infants. It is unknown how this parameter progresses in critically ill premature infants.
Aims: To investigate IVC oxygen saturation during the first three days of life in preterm infants with and without patent ductus arteriosus (PDA).
Study Design: Case-control study.
Methods: Twenty-seven preterm infants were admitted to the Neonatal Intensive Care. Preterm infants with umbilical venous catheterization were included in the study. Six umbilical venous blood gas values were obtained from each infant during the first 72 hours of life. Preterm infants in the study were divided into two groups. Haemodynamically significant PDA was diagnosed by echocardiography in 11 (41%) infants before the 72nd hour of life in the study group and ibuprofen treatment was started, whereas 16 (59%) infants who didn’t have haemodynamically significant PDA were included in the control group.
Results: In the entire group, the highest value of mean IVC oxygen saturation was 79.9% at the first measurement and the lowest was 64.8% at the 72nd hour. Inferior vena cava oxygen saturations were significantly different between the study and control groups. Post-hoc analysis revealed that the first and 36th hour measurements made the difference (p=0.01).
Conclusion: Inferior vena cava oxygen saturation was found to be significantly different between preterm infants with and without PDA. Further studies are needed to understand the effect of foetal shunts on venous oxygenation during postnatal adaptation in newborn infants. |
| first_indexed | 2024-04-10T14:41:59Z |
| format | Article |
| id | doaj.art-dba92b60613d4d79b44e08ba7ba449ae |
| institution | Directory Open Access Journal |
| issn | 2146-3123 2146-3131 |
| language | English |
| last_indexed | 2024-04-10T14:41:59Z |
| publishDate | 2014-09-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Balkan Medical Journal |
| spelling | doaj.art-dba92b60613d4d79b44e08ba7ba449ae2023-02-15T16:08:09ZengGalenos Publishing HouseBalkan Medical Journal2146-31232146-31312014-09-0131323023410.5152/balkanmedj.2014.13197Inferior Vena Cava Oxygen Saturation during the First Three Postnatal Days in Preterm Newborns with and without Patent Ductus ArteriosusEce Yapakçı0Ayşe Ecevit1Deniz Anuk İnce2Hande Gülcan3Aylin Tarcan4Mahmut Gökdemir5M. Agah Tekindal6Division of Neonatology, Department of Pediatrics, Başkent University Faculty of Medicine, Ankara, TurkeyDivision of Neonatology, Department of Pediatrics, Başkent University Faculty of Medicine, Ankara, TurkeyDivision of Neonatology, Department of Pediatrics, Başkent University Faculty of Medicine, Ankara, TurkeyDivision of Neonatology, Department of Pediatrics, Başkent University Faculty of Medicine, Ankara, TurkeyDivision of Neonatology, Department of Pediatrics, Başkent University Faculty of Medicine, Ankara, TurkeyDivision of Cardiology, Department of Pediatrics, Başkent University Faculty of Medicine, Ankara, TurkeyDepartment of Biostatistics, Başkent University Faculty of Medicine, Ankara, TurkeyBackground: Inferior vena cava (IVC) oxygen saturation as an indicator of mixed venous oxygenation may be valuable for understanding postnatal adaptations in newborn infants. It is unknown how this parameter progresses in critically ill premature infants. Aims: To investigate IVC oxygen saturation during the first three days of life in preterm infants with and without patent ductus arteriosus (PDA). Study Design: Case-control study. Methods: Twenty-seven preterm infants were admitted to the Neonatal Intensive Care. Preterm infants with umbilical venous catheterization were included in the study. Six umbilical venous blood gas values were obtained from each infant during the first 72 hours of life. Preterm infants in the study were divided into two groups. Haemodynamically significant PDA was diagnosed by echocardiography in 11 (41%) infants before the 72nd hour of life in the study group and ibuprofen treatment was started, whereas 16 (59%) infants who didn’t have haemodynamically significant PDA were included in the control group. Results: In the entire group, the highest value of mean IVC oxygen saturation was 79.9% at the first measurement and the lowest was 64.8% at the 72nd hour. Inferior vena cava oxygen saturations were significantly different between the study and control groups. Post-hoc analysis revealed that the first and 36th hour measurements made the difference (p=0.01). Conclusion: Inferior vena cava oxygen saturation was found to be significantly different between preterm infants with and without PDA. Further studies are needed to understand the effect of foetal shunts on venous oxygenation during postnatal adaptation in newborn infants.http://balkanmedicaljournal.org/text.php?lang=en&id=290Inferior vena cava oxygen saturationmixed venous oxygen saturationpatent ductus arteriosusprematurity |
| spellingShingle | Ece Yapakçı Ayşe Ecevit Deniz Anuk İnce Hande Gülcan Aylin Tarcan Mahmut Gökdemir M. Agah Tekindal Inferior Vena Cava Oxygen Saturation during the First Three Postnatal Days in Preterm Newborns with and without Patent Ductus Arteriosus Balkan Medical Journal Inferior vena cava oxygen saturation mixed venous oxygen saturation patent ductus arteriosus prematurity |
| title | Inferior Vena Cava Oxygen Saturation during the First Three Postnatal Days in Preterm Newborns with and without Patent Ductus Arteriosus |
| title_full | Inferior Vena Cava Oxygen Saturation during the First Three Postnatal Days in Preterm Newborns with and without Patent Ductus Arteriosus |
| title_fullStr | Inferior Vena Cava Oxygen Saturation during the First Three Postnatal Days in Preterm Newborns with and without Patent Ductus Arteriosus |
| title_full_unstemmed | Inferior Vena Cava Oxygen Saturation during the First Three Postnatal Days in Preterm Newborns with and without Patent Ductus Arteriosus |
| title_short | Inferior Vena Cava Oxygen Saturation during the First Three Postnatal Days in Preterm Newborns with and without Patent Ductus Arteriosus |
| title_sort | inferior vena cava oxygen saturation during the first three postnatal days in preterm newborns with and without patent ductus arteriosus |
| topic | Inferior vena cava oxygen saturation mixed venous oxygen saturation patent ductus arteriosus prematurity |
| url | http://balkanmedicaljournal.org/text.php?lang=en&id=290 |
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