Assessment of dyspneic sensation in patients with type 2 diabetes
IntroductionIndividuals with type 2 diabetes (T2D) should be considered a susceptible group for pulmonary dysfunction. So, we aimed to evaluate the sensation of breathlessness in this population by administering two well-validated questionnaires.MethodsThis is a crosssectional study with 592 people...
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Frontiers Media S.A.
2023-08-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2023.1208020/full |
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| author | Chadia Mizab Enric Sánchez Enric Sánchez Enric Sánchez Liliana Gutiérrez-Carrasquilla Núria Balsells Anaïs Arqué Raquel Ruano Raquel Ruano Magda Mateu Marta Zorzano-Martínez Marta Zorzano-Martínez Anna Pomés Esther García-Aguilera Raquel Martí Raquel Martí José María Manzanares Cristina Hernández Cristina Hernández Cristina Hernández Rafael Simó Rafael Simó Rafael Simó Albert Lecube Albert Lecube Albert Lecube |
| author_facet | Chadia Mizab Enric Sánchez Enric Sánchez Enric Sánchez Liliana Gutiérrez-Carrasquilla Núria Balsells Anaïs Arqué Raquel Ruano Raquel Ruano Magda Mateu Marta Zorzano-Martínez Marta Zorzano-Martínez Anna Pomés Esther García-Aguilera Raquel Martí Raquel Martí José María Manzanares Cristina Hernández Cristina Hernández Cristina Hernández Rafael Simó Rafael Simó Rafael Simó Albert Lecube Albert Lecube Albert Lecube |
| author_sort | Chadia Mizab |
| collection | DOAJ |
| description | IntroductionIndividuals with type 2 diabetes (T2D) should be considered a susceptible group for pulmonary dysfunction. So, we aimed to evaluate the sensation of breathlessness in this population by administering two well-validated questionnaires.MethodsThis is a crosssectional study with 592 people without known respiratory disease (353 with T2D) who answered the modified Medical Research Council (mMRC) questionnaire. In addition, 47% also responded to the St George Respiratory Questionnaire, a specific instrument designed to be applied to patients with obstructive airway disease.ResultsPatients with T2D showed a higher mMRC score in comparison to the control group [1.0 (0.0 – 4.0) vs. 0.0 (0.0 – 4.0), p<0.001]. A higher prevalence of subjects with mMRC ≥2 was observed in T2D that in the control group (20.2% vs. 11.6%, p=0.004). Participants with T2D and mMRC ≥2 showed a higher HbA1c (8.2 ± 1.6% vs. 7.8 ± 1.6%, p=0.048), longer T2D evolution and higher prevalence of nephropathy. In the multivariate analysis, the presence of T2D [OR=1.95 (1.19 to 3.22), p=0.008] in all the population, and HbA1c [OR=1.19 (1.01 to 1.41), p=0.034] and the presence of diabetic nephropathy [OR=2.00 (1.14 to 3.52), p=0.015] in patients with T2D, predicted a mMRC ≥2. Finally, no differences were observed regarding the SGRQ score among groups.ConclusionsPatients with T2D showed a greater sensation of dyspnea than subjects with normal carbohydrate metabolism. Risk factors included poor metabolic control and the presence of renal disease. |
| first_indexed | 2024-03-12T15:22:14Z |
| format | Article |
| id | doaj.art-dbaa23e04b7b4c23b1bc3dc49c7170f2 |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-03-12T15:22:14Z |
| publishDate | 2023-08-01 |
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| series | Frontiers in Endocrinology |
| spelling | doaj.art-dbaa23e04b7b4c23b1bc3dc49c7170f22023-08-11T01:18:57ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922023-08-011410.3389/fendo.2023.12080201208020Assessment of dyspneic sensation in patients with type 2 diabetesChadia Mizab0Enric Sánchez1Enric Sánchez2Enric Sánchez3Liliana Gutiérrez-Carrasquilla4Núria Balsells5Anaïs Arqué6Raquel Ruano7Raquel Ruano8Magda Mateu9Marta Zorzano-Martínez10Marta Zorzano-Martínez11Anna Pomés12Esther García-Aguilera13Raquel Martí14Raquel Martí15José María Manzanares16Cristina Hernández17Cristina Hernández18Cristina Hernández19Rafael Simó20Rafael Simó21Rafael Simó22Albert Lecube23Albert Lecube24Albert Lecube25Endocrinology and Nutrition Department, University Hospital Sant Joan de Reus, Reus, SpainEndocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Lleida, SpainObesity, Diabetes and Metabolism (ODIM) Research Group, Institut de Recerca Biomèdica de Lleida (IRBLleida), Lleida, SpainMedicine and Surgery Department, University of Lleida, Lleida, SpainEndocrinology and Nutrition Department, University Hospital Sant Joan de Reus, Reus, SpainEndocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Lleida, SpainEndocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Lleida, SpainEndocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Lleida, SpainObesity, Diabetes and Metabolism (ODIM) Research Group, Institut de Recerca Biomèdica de Lleida (IRBLleida), Lleida, SpainEndocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Lleida, SpainEndocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Lleida, SpainObesity, Diabetes and Metabolism (ODIM) Research Group, Institut de Recerca Biomèdica de Lleida (IRBLleida), Lleida, SpainEndocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Lleida, SpainEndocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Lleida, SpainEndocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Lleida, SpainObesity, Diabetes and Metabolism (ODIM) Research Group, Institut de Recerca Biomèdica de Lleida (IRBLleida), Lleida, SpainEndocrinology and Nutrition Department, University Hospital Sant Joan de Reus, Reus, SpainEndocrinology and Nutrition Department, Hospital Universitari Vall d’Hebron, Barcelona, SpainDiabetes and Metabolism Research Unit, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, SpainCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Madrid, SpainEndocrinology and Nutrition Department, Hospital Universitari Vall d’Hebron, Barcelona, SpainDiabetes and Metabolism Research Unit, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, SpainCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Madrid, SpainEndocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Lleida, SpainObesity, Diabetes and Metabolism (ODIM) Research Group, Institut de Recerca Biomèdica de Lleida (IRBLleida), Lleida, SpainMedicine and Surgery Department, University of Lleida, Lleida, SpainIntroductionIndividuals with type 2 diabetes (T2D) should be considered a susceptible group for pulmonary dysfunction. So, we aimed to evaluate the sensation of breathlessness in this population by administering two well-validated questionnaires.MethodsThis is a crosssectional study with 592 people without known respiratory disease (353 with T2D) who answered the modified Medical Research Council (mMRC) questionnaire. In addition, 47% also responded to the St George Respiratory Questionnaire, a specific instrument designed to be applied to patients with obstructive airway disease.ResultsPatients with T2D showed a higher mMRC score in comparison to the control group [1.0 (0.0 – 4.0) vs. 0.0 (0.0 – 4.0), p<0.001]. A higher prevalence of subjects with mMRC ≥2 was observed in T2D that in the control group (20.2% vs. 11.6%, p=0.004). Participants with T2D and mMRC ≥2 showed a higher HbA1c (8.2 ± 1.6% vs. 7.8 ± 1.6%, p=0.048), longer T2D evolution and higher prevalence of nephropathy. In the multivariate analysis, the presence of T2D [OR=1.95 (1.19 to 3.22), p=0.008] in all the population, and HbA1c [OR=1.19 (1.01 to 1.41), p=0.034] and the presence of diabetic nephropathy [OR=2.00 (1.14 to 3.52), p=0.015] in patients with T2D, predicted a mMRC ≥2. Finally, no differences were observed regarding the SGRQ score among groups.ConclusionsPatients with T2D showed a greater sensation of dyspnea than subjects with normal carbohydrate metabolism. Risk factors included poor metabolic control and the presence of renal disease.https://www.frontiersin.org/articles/10.3389/fendo.2023.1208020/fulldiabetes complicationsdyspneic sensationtype 2 diabetesrespiratory symptomsquestionnaires |
| spellingShingle | Chadia Mizab Enric Sánchez Enric Sánchez Enric Sánchez Liliana Gutiérrez-Carrasquilla Núria Balsells Anaïs Arqué Raquel Ruano Raquel Ruano Magda Mateu Marta Zorzano-Martínez Marta Zorzano-Martínez Anna Pomés Esther García-Aguilera Raquel Martí Raquel Martí José María Manzanares Cristina Hernández Cristina Hernández Cristina Hernández Rafael Simó Rafael Simó Rafael Simó Albert Lecube Albert Lecube Albert Lecube Assessment of dyspneic sensation in patients with type 2 diabetes Frontiers in Endocrinology diabetes complications dyspneic sensation type 2 diabetes respiratory symptoms questionnaires |
| title | Assessment of dyspneic sensation in patients with type 2 diabetes |
| title_full | Assessment of dyspneic sensation in patients with type 2 diabetes |
| title_fullStr | Assessment of dyspneic sensation in patients with type 2 diabetes |
| title_full_unstemmed | Assessment of dyspneic sensation in patients with type 2 diabetes |
| title_short | Assessment of dyspneic sensation in patients with type 2 diabetes |
| title_sort | assessment of dyspneic sensation in patients with type 2 diabetes |
| topic | diabetes complications dyspneic sensation type 2 diabetes respiratory symptoms questionnaires |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2023.1208020/full |
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