Malignant (Anaplastic) Amelanotic/Hypomelanotic Melanoma in a Kurdish Gelding

We report an 11-year-old Kurdish gelding with an anaplastic malignant melanoma arising from his right lateral of the neck, which developed over 6 weeks. A ~10 cm in diameter, firm, and non-ulcerated nodular subcutaneous mass located at the middle and proximal of the left side of the neck was detecte...

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Main Authors: Aram Sadi, Saeed Azizi, Hamed Masoudi
Format: Article
Language:English
Published: Iranian Veterinary Surgery Association (IVSA) 2021-10-01
Series:Iranian Journal of Veterinary Surgery
Subjects:
Online Access:http://www.ivsajournals.com/article_126963_0823562cf874d34c3184e197916e9a2b.pdf
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author Aram Sadi
Saeed Azizi
Hamed Masoudi
author_facet Aram Sadi
Saeed Azizi
Hamed Masoudi
author_sort Aram Sadi
collection DOAJ
description We report an 11-year-old Kurdish gelding with an anaplastic malignant melanoma arising from his right lateral of the neck, which developed over 6 weeks. A ~10 cm in diameter, firm, and non-ulcerated nodular subcutaneous mass located at the middle and proximal of the left side of the neck was detected in a physical examination. No evidence of local extent or metastasis was detected. Complete surgical excision was performed under general anesthesia. Gross morphology and histopathological examination of the mass confirmed an anaplastic malignant melanoma, in which the major part of the mass has little or no pigmentation. The gelding was euthanized due to tumor regrowth. The heterogeneity in pigmentation of equine melanocytic tumors can make diagnosis difficult in punch biopsy specimens. Anaplastic malignant melanoma is most often a very aggressive neoplasm and surgical excision was not effective in this case.
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spelling doaj.art-dbaa49890b6d4a7fa8047ba10888f3962022-12-21T20:45:44ZengIranian Veterinary Surgery Association (IVSA)Iranian Journal of Veterinary Surgery2008-30332676-62992021-10-0116214214510.30500/ivsa.2021.259636.1234126963Malignant (Anaplastic) Amelanotic/Hypomelanotic Melanoma in a Kurdish GeldingAram Sadi0Saeed Azizi1Hamed Masoudi2Department of Internal Medicine and Clinical Pathology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.Department of Surgery and Diagnostic Imaging, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.Department of Surgery and Diagnostic Imaging, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.We report an 11-year-old Kurdish gelding with an anaplastic malignant melanoma arising from his right lateral of the neck, which developed over 6 weeks. A ~10 cm in diameter, firm, and non-ulcerated nodular subcutaneous mass located at the middle and proximal of the left side of the neck was detected in a physical examination. No evidence of local extent or metastasis was detected. Complete surgical excision was performed under general anesthesia. Gross morphology and histopathological examination of the mass confirmed an anaplastic malignant melanoma, in which the major part of the mass has little or no pigmentation. The gelding was euthanized due to tumor regrowth. The heterogeneity in pigmentation of equine melanocytic tumors can make diagnosis difficult in punch biopsy specimens. Anaplastic malignant melanoma is most often a very aggressive neoplasm and surgical excision was not effective in this case.http://www.ivsajournals.com/article_126963_0823562cf874d34c3184e197916e9a2b.pdfanaplasticamelanoticpoorly pigmentedmalignant melanomaneckhorse
spellingShingle Aram Sadi
Saeed Azizi
Hamed Masoudi
Malignant (Anaplastic) Amelanotic/Hypomelanotic Melanoma in a Kurdish Gelding
Iranian Journal of Veterinary Surgery
anaplastic
amelanotic
poorly pigmented
malignant melanoma
neck
horse
title Malignant (Anaplastic) Amelanotic/Hypomelanotic Melanoma in a Kurdish Gelding
title_full Malignant (Anaplastic) Amelanotic/Hypomelanotic Melanoma in a Kurdish Gelding
title_fullStr Malignant (Anaplastic) Amelanotic/Hypomelanotic Melanoma in a Kurdish Gelding
title_full_unstemmed Malignant (Anaplastic) Amelanotic/Hypomelanotic Melanoma in a Kurdish Gelding
title_short Malignant (Anaplastic) Amelanotic/Hypomelanotic Melanoma in a Kurdish Gelding
title_sort malignant anaplastic amelanotic hypomelanotic melanoma in a kurdish gelding
topic anaplastic
amelanotic
poorly pigmented
malignant melanoma
neck
horse
url http://www.ivsajournals.com/article_126963_0823562cf874d34c3184e197916e9a2b.pdf
work_keys_str_mv AT aramsadi malignantanaplasticamelanotichypomelanoticmelanomainakurdishgelding
AT saeedazizi malignantanaplasticamelanotichypomelanoticmelanomainakurdishgelding
AT hamedmasoudi malignantanaplasticamelanotichypomelanoticmelanomainakurdishgelding