Oculus: faster sequence alignment by streaming read compression

<p>Abstract</p> <p>Background</p> <p>Despite significant advancement in alignment algorithms, the exponential growth of nucleotide sequencing throughput threatens to outpace bioinformatic analysis. Computation may become the bottleneck of genome analysis if growing alig...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Veeneman Brendan A, Iyer Matthew K, Chinnaiyan Arul M
Format: Artikel
Sprache:English
Veröffentlicht: BMC 2012-11-01
Schriftenreihe:BMC Bioinformatics
Schlagworte:
Online Zugang:http://www.biomedcentral.com/1471-2105/13/297