Quantification and qualification of complication risks at use of non-steroid anti-inflammatory drugs as a basis for recommendations on their use and prophylaxis

Non-steroid anti-inflammatory drugs (NSAID) were and still remain the main means for arresting acute and controlling chronic pains in therapeutic practice. However, serious complications that may be caused by these drugs essentially limit their application. Therapists need distinct and reasonable gu...

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Main Author: Andrey Evgenyevich Karateev
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2014-03-01
Series:Современная ревматология
Subjects:
Online Access:https://mrj.ima-press.net/mrj/article/view/513
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author Andrey Evgenyevich Karateev
author_facet Andrey Evgenyevich Karateev
author_sort Andrey Evgenyevich Karateev
collection DOAJ
description Non-steroid anti-inflammatory drugs (NSAID) were and still remain the main means for arresting acute and controlling chronic pains in therapeutic practice. However, serious complications that may be caused by these drugs essentially limit their application. Therapists need distinct and reasonable guidelines on NSAID prescription depending on presence of a comorbid pathology and risk factors associated with the gastrointestinal tract and cardiovascular system. World renowned experts have been actively studying this problem. The main aspects of NSAID efficiency and safety are discussed in this study; the risk factors are ranked according to their significance; and an algorithm of reasonable drug prescription, including prevention of potential complications, is proposed.
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spelling doaj.art-dbad7e37fedc45eb9203f6d7e87d75512023-03-13T08:39:23ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2014-03-0181647210.14412/1996-7012-2014-1-64-721818Quantification and qualification of complication risks at use of non-steroid anti-inflammatory drugs as a basis for recommendations on their use and prophylaxisAndrey Evgenyevich Karateev0ФГБУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой РАМН», Москва, Россия; 115522, Москва, Каширское шоссе, 34ANon-steroid anti-inflammatory drugs (NSAID) were and still remain the main means for arresting acute and controlling chronic pains in therapeutic practice. However, serious complications that may be caused by these drugs essentially limit their application. Therapists need distinct and reasonable guidelines on NSAID prescription depending on presence of a comorbid pathology and risk factors associated with the gastrointestinal tract and cardiovascular system. World renowned experts have been actively studying this problem. The main aspects of NSAID efficiency and safety are discussed in this study; the risk factors are ranked according to their significance; and an algorithm of reasonable drug prescription, including prevention of potential complications, is proposed.https://mrj.ima-press.net/mrj/article/view/513нестероидные противовоспалительные препаратыгастропатиякардиоваскулярные осложненияпрофилакти- кацелекоксибнапроксенингибиторы протонной помпынизкие дозы аспирина
spellingShingle Andrey Evgenyevich Karateev
Quantification and qualification of complication risks at use of non-steroid anti-inflammatory drugs as a basis for recommendations on their use and prophylaxis
Современная ревматология
нестероидные противовоспалительные препараты
гастропатия
кардиоваскулярные осложнения
профилакти- ка
целекоксиб
напроксен
ингибиторы протонной помпы
низкие дозы аспирина
title Quantification and qualification of complication risks at use of non-steroid anti-inflammatory drugs as a basis for recommendations on their use and prophylaxis
title_full Quantification and qualification of complication risks at use of non-steroid anti-inflammatory drugs as a basis for recommendations on their use and prophylaxis
title_fullStr Quantification and qualification of complication risks at use of non-steroid anti-inflammatory drugs as a basis for recommendations on their use and prophylaxis
title_full_unstemmed Quantification and qualification of complication risks at use of non-steroid anti-inflammatory drugs as a basis for recommendations on their use and prophylaxis
title_short Quantification and qualification of complication risks at use of non-steroid anti-inflammatory drugs as a basis for recommendations on their use and prophylaxis
title_sort quantification and qualification of complication risks at use of non steroid anti inflammatory drugs as a basis for recommendations on their use and prophylaxis
topic нестероидные противовоспалительные препараты
гастропатия
кардиоваскулярные осложнения
профилакти- ка
целекоксиб
напроксен
ингибиторы протонной помпы
низкие дозы аспирина
url https://mrj.ima-press.net/mrj/article/view/513
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