Identification of a cytotoxic form of dimeric interleukin-2 in murine tissues.

Identification of a cytotoxic form of dimeric interleukin-2 in murine tissues.

Interleukin-2 (IL-2) is a multi-faceted cytokine, known for promoting proliferation, survival, and cell death depending on the cell type and state. For example, IL-2 facilitates cell death only in activated T cells when antigen and IL-2 are abundant. The availability of IL-2 clearly impacts this pro...

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Hlavní autoři: Lucile E Wrenshall, Suzanne E Clabaugh, David R Cool, Prakash Arumugam, William C Grunwald, Deandra R Smith, Gino C Liu, John D Miller
Médium: Článek
Jazyk:English
Vydáno: Public Library of Science (PLoS) 2014-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC4097599?pdf=render

Internet

http://europepmc.org/articles/PMC4097599?pdf=render

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