The chemokine receptor CCR5, a therapeutic target for HIV/AIDS antagonists, is critical for recovery in a mouse model of Japanese encephalitis.
Japanese encephalitis is a severe central nervous system (CNS) inflammatory disease caused by the mosquito-borne flavivirus, Japanese encephalitis virus (JEV). In the current study we have investigated the immune responses against JEV in mice lacking expression of the chemokine receptor CCR5, which...
| Auteurs principaux: | , , |
|---|---|
| Format: | Article |
| Langue: | English |
| Publié: |
Public Library of Science (PLoS)
2012-01-01
|
| Collection: | PLoS ONE |
| Accès en ligne: | http://europepmc.org/articles/PMC3448613?pdf=render |