Safe Pseudovirus-based Assay for Neutralization Antibodies against Influenza A(H7N9) Virus
Serologic studies are urgently needed to assist in understanding an outbreak of influenza A(H7N9) virus. However, a biosafety level 3 laboratory is required for conventional serologic assays with live lethal virus. We describe a safe pseudovirus–based neutralization assay with preliminary assessment...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
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Centers for Disease Control and Prevention
2013-10-01
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Series: | Emerging Infectious Diseases |
Subjects: | |
Online Access: | https://wwwnc.cdc.gov/eid/article/19/10/13-0728_article |
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author | Chao Qiu Yang Huang Anli Zhang Di Tian Yanmin Wan Xiaoling Zhang Wanju Zhang Zhiyong Zhang Zhenghong Yuan Yunwen Hu Xiaoyan Zhang Jianqing Xu |
author_facet | Chao Qiu Yang Huang Anli Zhang Di Tian Yanmin Wan Xiaoling Zhang Wanju Zhang Zhiyong Zhang Zhenghong Yuan Yunwen Hu Xiaoyan Zhang Jianqing Xu |
author_sort | Chao Qiu |
collection | DOAJ |
description | Serologic studies are urgently needed to assist in understanding an outbreak of influenza A(H7N9) virus. However, a biosafety level 3 laboratory is required for conventional serologic assays with live lethal virus. We describe a safe pseudovirus–based neutralization assay with preliminary assessment using subtype H7N9–infected samples and controls. |
first_indexed | 2024-12-22T17:51:13Z |
format | Article |
id | doaj.art-dbb27cdc8905430388c8ac640c693041 |
institution | Directory Open Access Journal |
issn | 1080-6040 1080-6059 |
language | English |
last_indexed | 2024-12-22T17:51:13Z |
publishDate | 2013-10-01 |
publisher | Centers for Disease Control and Prevention |
record_format | Article |
series | Emerging Infectious Diseases |
spelling | doaj.art-dbb27cdc8905430388c8ac640c6930412022-12-21T18:18:10ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592013-10-0119101685168710.3201/eid1910.130728Safe Pseudovirus-based Assay for Neutralization Antibodies against Influenza A(H7N9) VirusChao QiuYang HuangAnli ZhangDi TianYanmin WanXiaoling ZhangWanju ZhangZhiyong ZhangZhenghong YuanYunwen HuXiaoyan ZhangJianqing XuSerologic studies are urgently needed to assist in understanding an outbreak of influenza A(H7N9) virus. However, a biosafety level 3 laboratory is required for conventional serologic assays with live lethal virus. We describe a safe pseudovirus–based neutralization assay with preliminary assessment using subtype H7N9–infected samples and controls.https://wwwnc.cdc.gov/eid/article/19/10/13-0728_articleInfluenzasubtype H7N9serologyneutralization testspseudovirusviruses |
spellingShingle | Chao Qiu Yang Huang Anli Zhang Di Tian Yanmin Wan Xiaoling Zhang Wanju Zhang Zhiyong Zhang Zhenghong Yuan Yunwen Hu Xiaoyan Zhang Jianqing Xu Safe Pseudovirus-based Assay for Neutralization Antibodies against Influenza A(H7N9) Virus Emerging Infectious Diseases Influenza subtype H7N9 serology neutralization tests pseudovirus viruses |
title | Safe Pseudovirus-based Assay for Neutralization Antibodies against Influenza A(H7N9) Virus |
title_full | Safe Pseudovirus-based Assay for Neutralization Antibodies against Influenza A(H7N9) Virus |
title_fullStr | Safe Pseudovirus-based Assay for Neutralization Antibodies against Influenza A(H7N9) Virus |
title_full_unstemmed | Safe Pseudovirus-based Assay for Neutralization Antibodies against Influenza A(H7N9) Virus |
title_short | Safe Pseudovirus-based Assay for Neutralization Antibodies against Influenza A(H7N9) Virus |
title_sort | safe pseudovirus based assay for neutralization antibodies against influenza a h7n9 virus |
topic | Influenza subtype H7N9 serology neutralization tests pseudovirus viruses |
url | https://wwwnc.cdc.gov/eid/article/19/10/13-0728_article |
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