Spindle power is not affected after spontaneous K-complexes during human NREM sleep.
K-complexes and sleep spindles often grouped together characterize the second stage of NREM sleep and interest has been raised on a possible interaction of their underlying mechanisms. The reported inhibition of spindles power for about 15 seconds following evoked K-complexes has implications on the...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2013-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23326604/pdf/?tool=EBI |
| _version_ | 1818459575055024128 |
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| author | Andreas M Koupparis Vasileios Kokkinos George K Kostopoulos |
| author_facet | Andreas M Koupparis Vasileios Kokkinos George K Kostopoulos |
| author_sort | Andreas M Koupparis |
| collection | DOAJ |
| description | K-complexes and sleep spindles often grouped together characterize the second stage of NREM sleep and interest has been raised on a possible interaction of their underlying mechanisms. The reported inhibition of spindles power for about 15 seconds following evoked K-complexes has implications on their role in arousal. Our objective was to assess this inhibition following spontaneous K-complexes. We used time-frequency analysis of spontaneous K-complexes selected from whole-night EEG recordings of normal subjects. Our results show that spindles are most often observed at the positive phase following the peak of a spontaneous KC (70%). At latencies of 1-3 s following the peak of the K-complex, spindles almost disappear. Compared to long-term effects described for evoked KCs, sleep spindle power is not affected by spontaneous KCs for latencies of 5-15 s. Observation of the recurrence rate of sporadic spindles suggests that the reduction of power at 1-3 s most likely reflects a refractory period of spindles lasting for 1-2 s, rather than an effect of KCs. These results suggest that the mechanisms underlying spontaneous KCs do not affect spindle power as in the case of evoked KCs. |
| first_indexed | 2024-12-14T23:16:32Z |
| format | Article |
| id | doaj.art-dbb36d877f6d4b86af4a43f3cf44aa8c |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-14T23:16:32Z |
| publishDate | 2013-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-dbb36d877f6d4b86af4a43f3cf44aa8c2022-12-21T22:44:04ZengPublic Library of Science (PLoS)PLoS ONE1932-62032013-01-0181e5434310.1371/journal.pone.0054343Spindle power is not affected after spontaneous K-complexes during human NREM sleep.Andreas M KoupparisVasileios KokkinosGeorge K KostopoulosK-complexes and sleep spindles often grouped together characterize the second stage of NREM sleep and interest has been raised on a possible interaction of their underlying mechanisms. The reported inhibition of spindles power for about 15 seconds following evoked K-complexes has implications on their role in arousal. Our objective was to assess this inhibition following spontaneous K-complexes. We used time-frequency analysis of spontaneous K-complexes selected from whole-night EEG recordings of normal subjects. Our results show that spindles are most often observed at the positive phase following the peak of a spontaneous KC (70%). At latencies of 1-3 s following the peak of the K-complex, spindles almost disappear. Compared to long-term effects described for evoked KCs, sleep spindle power is not affected by spontaneous KCs for latencies of 5-15 s. Observation of the recurrence rate of sporadic spindles suggests that the reduction of power at 1-3 s most likely reflects a refractory period of spindles lasting for 1-2 s, rather than an effect of KCs. These results suggest that the mechanisms underlying spontaneous KCs do not affect spindle power as in the case of evoked KCs.https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23326604/pdf/?tool=EBI |
| spellingShingle | Andreas M Koupparis Vasileios Kokkinos George K Kostopoulos Spindle power is not affected after spontaneous K-complexes during human NREM sleep. PLoS ONE |
| title | Spindle power is not affected after spontaneous K-complexes during human NREM sleep. |
| title_full | Spindle power is not affected after spontaneous K-complexes during human NREM sleep. |
| title_fullStr | Spindle power is not affected after spontaneous K-complexes during human NREM sleep. |
| title_full_unstemmed | Spindle power is not affected after spontaneous K-complexes during human NREM sleep. |
| title_short | Spindle power is not affected after spontaneous K-complexes during human NREM sleep. |
| title_sort | spindle power is not affected after spontaneous k complexes during human nrem sleep |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23326604/pdf/?tool=EBI |
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