The effect of metformin on senescence of T lymphocytes

Abstract Background Immunosenescence occurs as people age, leading to an increased incidence of age-related diseases. The number of senescent T cells also rises with age. T cell senescence and immune response dysfunction can result in a decline in immune function, especially in anti-tumor immune res...

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Main Authors: Jia Yang, Hai-Cheng Liu, Jian-Qing Zhang, Jian-Yong Zou, Xin Zhang, Wo-Ming Chen, Yong Gu, Hai Hong
פורמט: Article
שפה:English
יצא לאור: BMC 2023-12-01
סדרה:Immunity & Ageing
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גישה מקוונת:https://doi.org/10.1186/s12979-023-00394-0