Sella Turcica Atypical Teratoid/Rhabdoid Tumor Complicated with Lung Metastasis in an Adult Female
Here we present the case of a 60-year-old woman with a rare sellar region atypical teratoid/rhabdoid tumor (AT/RT), complicated by lung metastasis and treated with neurosurgery, radiotherapy, and chemotherapy. The patient had recurrent headache associated with left cavernous sinus syndrome after a p...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2013-01-01
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| Series: | Clinical Medicine Insights: Case Reports |
| Online Access: | https://doi.org/10.4137/CCRep.S12834 |
| _version_ | 1828939392525271040 |
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| author | Costanzo Moretti Domenico Lupoi Francesca Spasaro Laura Chioma Paola Di Giacinto Martina Colicchia Mario Frajoli Renzo Mocini Salvatore Ulisse Manila Antonelli Felice Giangaspero Lucio Gnessi |
| author_facet | Costanzo Moretti Domenico Lupoi Francesca Spasaro Laura Chioma Paola Di Giacinto Martina Colicchia Mario Frajoli Renzo Mocini Salvatore Ulisse Manila Antonelli Felice Giangaspero Lucio Gnessi |
| author_sort | Costanzo Moretti |
| collection | DOAJ |
| description | Here we present the case of a 60-year-old woman with a rare sellar region atypical teratoid/rhabdoid tumor (AT/RT), complicated by lung metastasis and treated with neurosurgery, radiotherapy, and chemotherapy. The patient had recurrent headache associated with left cavernous sinus syndrome after a previous endonasal transsphenoidal resection for a presumptive pituitary macroadenoma. Pituitary magnetic resonance imaging showed a tumor regrowth in the original location with a haemorrhagic component involving the left cavernous sinus. A near complete transsphenoidal resection of the sellar mass was performed followed by 3 months of stereotactic radiotherapy. Because of a worsening of the general clinical conditions, respiratory failure, and asthenia, the patient underwent a contrast enhanced computer tomography of the whole body which showed the presence of lung metastasis. The histopathological diagnosis on samples from pituitary and lung tissues was AT/RT. The patient survived 30 months after diagnosis regardless chemotherapy. In the adult, the AT/RT should be considered as a possible rare, aggressive, and malignant neoplasm localized in the sella turcica. |
| first_indexed | 2024-12-14T03:00:51Z |
| format | Article |
| id | doaj.art-dbbe1f9a75d7480f8e0327a52d9516c1 |
| institution | Directory Open Access Journal |
| issn | 1179-5476 |
| language | English |
| last_indexed | 2024-12-14T03:00:51Z |
| publishDate | 2013-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical Medicine Insights: Case Reports |
| spelling | doaj.art-dbbe1f9a75d7480f8e0327a52d9516c12022-12-21T23:19:31ZengSAGE PublishingClinical Medicine Insights: Case Reports1179-54762013-01-01610.4137/CCRep.S12834Sella Turcica Atypical Teratoid/Rhabdoid Tumor Complicated with Lung Metastasis in an Adult FemaleCostanzo Moretti0Domenico Lupoi1Francesca Spasaro2Laura Chioma3Paola Di Giacinto4Martina Colicchia5Mario Frajoli6Renzo Mocini7Salvatore Ulisse8Manila Antonelli9Felice Giangaspero10Lucio Gnessi11Unit of Endocrinology and Diabetes, Section of Reproductive Endocrinology University of Tor Vergata, San Giovanni Calibita Fatebenefratelli Hospital Tiber Island, Rome, Italy.Radiology Unit, San Giovanni Calibita Fatebenefratelli Hospital Tiber Island, Rome, Italy.Unit of Endocrinology and Diabetes, Section of Reproductive Endocrinology University of Tor Vergata, San Giovanni Calibita Fatebenefratelli Hospital Tiber Island, Rome, Italy.Unit of Endocrinology and Diabetes, Section of Reproductive Endocrinology University of Tor Vergata, San Giovanni Calibita Fatebenefratelli Hospital Tiber Island, Rome, Italy.Unit of Endocrinology and Diabetes, Section of Reproductive Endocrinology University of Tor Vergata, San Giovanni Calibita Fatebenefratelli Hospital Tiber Island, Rome, Italy.Unit of Endocrinology and Diabetes, Section of Reproductive Endocrinology University of Tor Vergata, San Giovanni Calibita Fatebenefratelli Hospital Tiber Island, Rome, Italy.Unit of Neurosurgery, Policlinico of Tor Vergata, Rome, Italy.Department of Surgical Sciences, “Sapienza” University of Rome, Italy.Department of Experimental Medicine, “Sapienza” University of Rome, Italy.Department of Radiology, Oncology and Pathological Sciences, “Sapienza” University of Rome, Italy.Department of Radiology, Oncology and Pathological Sciences, “Sapienza” University of Rome, Italy.Department of Experimental Medicine, “Sapienza” University of Rome, Italy.Here we present the case of a 60-year-old woman with a rare sellar region atypical teratoid/rhabdoid tumor (AT/RT), complicated by lung metastasis and treated with neurosurgery, radiotherapy, and chemotherapy. The patient had recurrent headache associated with left cavernous sinus syndrome after a previous endonasal transsphenoidal resection for a presumptive pituitary macroadenoma. Pituitary magnetic resonance imaging showed a tumor regrowth in the original location with a haemorrhagic component involving the left cavernous sinus. A near complete transsphenoidal resection of the sellar mass was performed followed by 3 months of stereotactic radiotherapy. Because of a worsening of the general clinical conditions, respiratory failure, and asthenia, the patient underwent a contrast enhanced computer tomography of the whole body which showed the presence of lung metastasis. The histopathological diagnosis on samples from pituitary and lung tissues was AT/RT. The patient survived 30 months after diagnosis regardless chemotherapy. In the adult, the AT/RT should be considered as a possible rare, aggressive, and malignant neoplasm localized in the sella turcica.https://doi.org/10.4137/CCRep.S12834 |
| spellingShingle | Costanzo Moretti Domenico Lupoi Francesca Spasaro Laura Chioma Paola Di Giacinto Martina Colicchia Mario Frajoli Renzo Mocini Salvatore Ulisse Manila Antonelli Felice Giangaspero Lucio Gnessi Sella Turcica Atypical Teratoid/Rhabdoid Tumor Complicated with Lung Metastasis in an Adult Female Clinical Medicine Insights: Case Reports |
| title | Sella Turcica Atypical Teratoid/Rhabdoid Tumor Complicated with Lung Metastasis in an Adult Female |
| title_full | Sella Turcica Atypical Teratoid/Rhabdoid Tumor Complicated with Lung Metastasis in an Adult Female |
| title_fullStr | Sella Turcica Atypical Teratoid/Rhabdoid Tumor Complicated with Lung Metastasis in an Adult Female |
| title_full_unstemmed | Sella Turcica Atypical Teratoid/Rhabdoid Tumor Complicated with Lung Metastasis in an Adult Female |
| title_short | Sella Turcica Atypical Teratoid/Rhabdoid Tumor Complicated with Lung Metastasis in an Adult Female |
| title_sort | sella turcica atypical teratoid rhabdoid tumor complicated with lung metastasis in an adult female |
| url | https://doi.org/10.4137/CCRep.S12834 |
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