Collagen patch cover facilitates recovery of bowel function after laparoscopic colectomy
Abstract Background Numerous factors can influence bowel movement recovery and anastomotic healing in colorectal surgery, and poor healing can lead to severe complications and increased medical expenses. Collagen patch cover (CPC) is a promising biomaterial that has been demonstrated to be safe in a...
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| Format: | Article |
| Language: | English |
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BMC
2024-02-01
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| Series: | BMC Surgery |
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| Online Access: | https://doi.org/10.1186/s12893-024-02339-w |
| _version_ | 1827328850077417472 |
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| author | Pin-Yang Huang Meng-Che Tsai Kee-Thai Kiu Min-Hsuan Yen Tung-Cheng Chang |
| author_facet | Pin-Yang Huang Meng-Che Tsai Kee-Thai Kiu Min-Hsuan Yen Tung-Cheng Chang |
| author_sort | Pin-Yang Huang |
| collection | DOAJ |
| description | Abstract Background Numerous factors can influence bowel movement recovery and anastomotic healing in colorectal surgery, and poor healing can lead to severe complications and increased medical expenses. Collagen patch cover (CPC) is a promising biomaterial that has been demonstrated to be safe in animal models and has been successfully applied in various surgical procedures in humans. This study. Methods A retrospective review of medical records from July 2020 to June 2022 was conducted to identify consecutive patients who underwent laparoscopic colectomy. Patients who received CPC at the anastomotic site were assigned to the collagen group, whereas those who did not receive CPC were assigned to the control group. Results Data from 241 patients (collagen group, 109; control group, 132) were analyzed. Relative to the control group, the collagen group exhibited a faster recovery of bowel function, including an earlier onset of first flatus (2.93 days vs. 3.43 days, p < 0.01), first defecation (3.73 days vs. 4.18 days, p = 0.01), and oral intake (4.30 days vs. 4.68 days, p = 0.04). CPC use was also associated with lower use of postoperative intravenous analgesics. The complication rates in the two groups did not differ significantly. Conclusions CPCs can be safely and easily applied to the anastomotic site during laparoscopic colectomy, and can accelerate bowel movement recovery. Further studies on the effectiveness of CPCs in colorectal surgery involving larger sample sizes are required. Clinical trial registration ClinicalTrials.gov registration number: NCT05831956 (26/04/2023). |
| first_indexed | 2024-03-07T15:23:20Z |
| format | Article |
| id | doaj.art-dbbf28d202234e9cba70ab2ba7048615 |
| institution | Directory Open Access Journal |
| issn | 1471-2482 |
| language | English |
| last_indexed | 2024-03-07T15:23:20Z |
| publishDate | 2024-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Surgery |
| spelling | doaj.art-dbbf28d202234e9cba70ab2ba70486152024-03-05T17:31:02ZengBMCBMC Surgery1471-24822024-02-012411910.1186/s12893-024-02339-wCollagen patch cover facilitates recovery of bowel function after laparoscopic colectomyPin-Yang Huang0Meng-Che Tsai1Kee-Thai Kiu2Min-Hsuan Yen3Tung-Cheng Chang4Department of General Medicine, Taipei Medical University Shuang-Ho HospitalDepartment of General Medicine, Chiayi Chang Gung Memorial Hospital, Chiayi CountyDivision of Colorectal Surgery, Department of Surgery, Taipei Medical University Shuang-Ho HospitalDivision of Colorectal Surgery, Department of Surgery, Taipei Medical University Shuang-Ho HospitalDivision of Colorectal Surgery, Department of Surgery, Taipei Medical University Shuang-Ho HospitalAbstract Background Numerous factors can influence bowel movement recovery and anastomotic healing in colorectal surgery, and poor healing can lead to severe complications and increased medical expenses. Collagen patch cover (CPC) is a promising biomaterial that has been demonstrated to be safe in animal models and has been successfully applied in various surgical procedures in humans. This study. Methods A retrospective review of medical records from July 2020 to June 2022 was conducted to identify consecutive patients who underwent laparoscopic colectomy. Patients who received CPC at the anastomotic site were assigned to the collagen group, whereas those who did not receive CPC were assigned to the control group. Results Data from 241 patients (collagen group, 109; control group, 132) were analyzed. Relative to the control group, the collagen group exhibited a faster recovery of bowel function, including an earlier onset of first flatus (2.93 days vs. 3.43 days, p < 0.01), first defecation (3.73 days vs. 4.18 days, p = 0.01), and oral intake (4.30 days vs. 4.68 days, p = 0.04). CPC use was also associated with lower use of postoperative intravenous analgesics. The complication rates in the two groups did not differ significantly. Conclusions CPCs can be safely and easily applied to the anastomotic site during laparoscopic colectomy, and can accelerate bowel movement recovery. Further studies on the effectiveness of CPCs in colorectal surgery involving larger sample sizes are required. Clinical trial registration ClinicalTrials.gov registration number: NCT05831956 (26/04/2023).https://doi.org/10.1186/s12893-024-02339-wCollagen patch coverBowel recoveryLaparoscopic colectomy |
| spellingShingle | Pin-Yang Huang Meng-Che Tsai Kee-Thai Kiu Min-Hsuan Yen Tung-Cheng Chang Collagen patch cover facilitates recovery of bowel function after laparoscopic colectomy BMC Surgery Collagen patch cover Bowel recovery Laparoscopic colectomy |
| title | Collagen patch cover facilitates recovery of bowel function after laparoscopic colectomy |
| title_full | Collagen patch cover facilitates recovery of bowel function after laparoscopic colectomy |
| title_fullStr | Collagen patch cover facilitates recovery of bowel function after laparoscopic colectomy |
| title_full_unstemmed | Collagen patch cover facilitates recovery of bowel function after laparoscopic colectomy |
| title_short | Collagen patch cover facilitates recovery of bowel function after laparoscopic colectomy |
| title_sort | collagen patch cover facilitates recovery of bowel function after laparoscopic colectomy |
| topic | Collagen patch cover Bowel recovery Laparoscopic colectomy |
| url | https://doi.org/10.1186/s12893-024-02339-w |
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