STAPHYLOCOCCAL SCALDED SKIN SYNDROME MIMICKING TOXIC EPIDERMAL NECROLYSIS IN A HEALTHY ADULT

Introduction: Staphylococcal scaled skin syndrome (SSSS) presents generalized form bullous impetigo caused by Staphylococcus aureus (S. aureus) infection, typically seen in infants and children. SSSS may occur also in adults; however, the majority of adult cases are those with immunosuppression. Aty...

Full description

Bibliographic Details
Main Authors: Tomoko Oishi, Yuka Hanami, Yasunobu Kato, Mikio Otsuka, Toshiyuki Yamamoto
Format: Article
Language:English
Published: Our Dermatology Online 2013-07-01
Series:Nasza Dermatologia Online
Subjects:
Online Access:http://www.odermatol.com/issue-in-html/2013-3-22-staphylococcal/
_version_ 1818228567263150080
author Tomoko Oishi
Yuka Hanami
Yasunobu Kato
Mikio Otsuka
Toshiyuki Yamamoto
author_facet Tomoko Oishi
Yuka Hanami
Yasunobu Kato
Mikio Otsuka
Toshiyuki Yamamoto
author_sort Tomoko Oishi
collection DOAJ
description Introduction: Staphylococcal scaled skin syndrome (SSSS) presents generalized form bullous impetigo caused by Staphylococcus aureus (S. aureus) infection, typically seen in infants and children. SSSS may occur also in adults; however, the majority of adult cases are those with immunosuppression. Atypical clinical features of impetigo in adults sometimes make it difficult to diagnose correctly. Case Report: A 74-year-old healthy woman was hospitalized, complaining of extensive desquamative erythema and a number of erosions. She was administered oral antiviral drugs under suspicion of herpes zoster prior to 10 days. Initial diagnosis on the admission was toxic epidermal necrolysis (TEN) due to antiviral tablets; however, steroid pulse therapy resulted in no effect. Bacterial culture yielded coagulase-positive methicillin-resistent S. aureus, producing exfoliative toxin B. A biopsy specimen showed subcorneal splitting of the epidermis. The diffuse erosions gradually improved over 10 days by the treatment with intravenous antibiotics. Conclusions: The differentiation between streptococcal scaled skin syndrome (SSSS) and TEN is sometimes difficult. It is important to remind SSSS when we suspect TEN, even in healthy adults..
first_indexed 2024-12-12T10:04:45Z
format Article
id doaj.art-dbc04b3f41d14719945188d4f3336cb3
institution Directory Open Access Journal
issn 2081-9390
language English
last_indexed 2024-12-12T10:04:45Z
publishDate 2013-07-01
publisher Our Dermatology Online
record_format Article
series Nasza Dermatologia Online
spelling doaj.art-dbc04b3f41d14719945188d4f3336cb32022-12-22T00:27:55ZengOur Dermatology OnlineNasza Dermatologia Online2081-93902013-07-014334734810.7241/ourd.20133.86STAPHYLOCOCCAL SCALDED SKIN SYNDROME MIMICKING TOXIC EPIDERMAL NECROLYSIS IN A HEALTHY ADULTTomoko OishiYuka HanamiYasunobu KatoMikio OtsukaToshiyuki YamamotoIntroduction: Staphylococcal scaled skin syndrome (SSSS) presents generalized form bullous impetigo caused by Staphylococcus aureus (S. aureus) infection, typically seen in infants and children. SSSS may occur also in adults; however, the majority of adult cases are those with immunosuppression. Atypical clinical features of impetigo in adults sometimes make it difficult to diagnose correctly. Case Report: A 74-year-old healthy woman was hospitalized, complaining of extensive desquamative erythema and a number of erosions. She was administered oral antiviral drugs under suspicion of herpes zoster prior to 10 days. Initial diagnosis on the admission was toxic epidermal necrolysis (TEN) due to antiviral tablets; however, steroid pulse therapy resulted in no effect. Bacterial culture yielded coagulase-positive methicillin-resistent S. aureus, producing exfoliative toxin B. A biopsy specimen showed subcorneal splitting of the epidermis. The diffuse erosions gradually improved over 10 days by the treatment with intravenous antibiotics. Conclusions: The differentiation between streptococcal scaled skin syndrome (SSSS) and TEN is sometimes difficult. It is important to remind SSSS when we suspect TEN, even in healthy adults..http://www.odermatol.com/issue-in-html/2013-3-22-staphylococcal/SSSSTENMRSAadult
spellingShingle Tomoko Oishi
Yuka Hanami
Yasunobu Kato
Mikio Otsuka
Toshiyuki Yamamoto
STAPHYLOCOCCAL SCALDED SKIN SYNDROME MIMICKING TOXIC EPIDERMAL NECROLYSIS IN A HEALTHY ADULT
Nasza Dermatologia Online
SSSS
TEN
MRSA
adult
title STAPHYLOCOCCAL SCALDED SKIN SYNDROME MIMICKING TOXIC EPIDERMAL NECROLYSIS IN A HEALTHY ADULT
title_full STAPHYLOCOCCAL SCALDED SKIN SYNDROME MIMICKING TOXIC EPIDERMAL NECROLYSIS IN A HEALTHY ADULT
title_fullStr STAPHYLOCOCCAL SCALDED SKIN SYNDROME MIMICKING TOXIC EPIDERMAL NECROLYSIS IN A HEALTHY ADULT
title_full_unstemmed STAPHYLOCOCCAL SCALDED SKIN SYNDROME MIMICKING TOXIC EPIDERMAL NECROLYSIS IN A HEALTHY ADULT
title_short STAPHYLOCOCCAL SCALDED SKIN SYNDROME MIMICKING TOXIC EPIDERMAL NECROLYSIS IN A HEALTHY ADULT
title_sort staphylococcal scalded skin syndrome mimicking toxic epidermal necrolysis in a healthy adult
topic SSSS
TEN
MRSA
adult
url http://www.odermatol.com/issue-in-html/2013-3-22-staphylococcal/
work_keys_str_mv AT tomokooishi staphylococcalscaldedskinsyndromemimickingtoxicepidermalnecrolysisinahealthyadult
AT yukahanami staphylococcalscaldedskinsyndromemimickingtoxicepidermalnecrolysisinahealthyadult
AT yasunobukato staphylococcalscaldedskinsyndromemimickingtoxicepidermalnecrolysisinahealthyadult
AT mikiootsuka staphylococcalscaldedskinsyndromemimickingtoxicepidermalnecrolysisinahealthyadult
AT toshiyukiyamamoto staphylococcalscaldedskinsyndromemimickingtoxicepidermalnecrolysisinahealthyadult