PRT to predict pharmacokinetic profiles as part of a bioequivalence study of the drug deferasirox

Introduction. Deferasirox is a complexing drug and belongs to class II according to the biopharmaceutical classification system (BCS), has acidic properties and belongs to subclass “a” (acid). This class is characterized by high permeability and low solubility, which limits the absorption of the act...

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Main Authors: A. V. Suvorova, P. A. Losenkova, Yu. V. Medvedev, E. A. Malashenko, I. E. Makarenko, A. M. Poluyanov, I. E. Shohin
格式: Article
語言:Russian
出版: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2024-09-01
叢編:Разработка и регистрация лекарственных средств
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在線閱讀:https://www.pharmjournal.ru/jour/article/view/1914