Gingerols and shogaols: A multi-faceted review of their extraction, formulation, and analysis in drugs and biofluids to maximize their nutraceutical and pharmaceutical applications
Gingerols represent the main bioactive compounds in ginger drugs mostly Zinigiber officinale (F. Zingebraceae) and account for the biological activities and the strong/pungent flavor in ginger. Ginger (Z. officinale) rhizome is one of the most valued herbal drugs for ailments’ treatment in many ayur...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-12-01
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| Series: | Food Chemistry: X |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590157523003905 |
| _version_ | 1797383725740195840 |
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| author | Yasmin R. Maghraby Rola M. Labib Mansour Sobeh Mohamed A. Farag |
| author_facet | Yasmin R. Maghraby Rola M. Labib Mansour Sobeh Mohamed A. Farag |
| author_sort | Yasmin R. Maghraby |
| collection | DOAJ |
| description | Gingerols represent the main bioactive compounds in ginger drugs mostly Zinigiber officinale (F. Zingebraceae) and account for the biological activities and the strong/pungent flavor in ginger. Ginger (Z. officinale) rhizome is one of the most valued herbal drugs for ailments’ treatment in many ayurvedic medicine asides from its culinary applications as a spice. Gingerols and their dehydrated products shogaols are phenolic phytochemicals found in members of the Zingiberaceae family and account for most of their effects including anti-inflammatory and anticancer activities. This review entails most of the novel trends related to the extraction, optimization, and formulations of gingerols and shogaols to insure best recoveries and efficacies from their natural resources. Further, it presents a comprehensive overview of the different analytical approaches for the determination of gingerols/shogaols’ levels in nutraceuticals to ensure highest quality and for their detection in body fluids for proof of efficacy. |
| first_indexed | 2024-03-08T21:25:34Z |
| format | Article |
| id | doaj.art-dbc22ac677e345f280b88cc103a7de39 |
| institution | Directory Open Access Journal |
| issn | 2590-1575 |
| language | English |
| last_indexed | 2024-03-08T21:25:34Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Chemistry: X |
| spelling | doaj.art-dbc22ac677e345f280b88cc103a7de392023-12-21T07:36:41ZengElsevierFood Chemistry: X2590-15752023-12-0120100947Gingerols and shogaols: A multi-faceted review of their extraction, formulation, and analysis in drugs and biofluids to maximize their nutraceutical and pharmaceutical applicationsYasmin R. Maghraby0Rola M. Labib1Mansour Sobeh2Mohamed A. Farag3Department of Chemistry, The American University in Cairo, New Cairo, EgyptPharmacognosy Department, Faculty of Pharmacy, Ain Shams University, Cairo, EgyptAgroBioSciences Program, Mohammed VI Polytechnic University, Lot 660, Hay Moulay Rachid, Ben-Guerir 43150, MoroccoPharmacognosy Department, College of Pharmacy, Cairo University, Cairo, Egypt; Corresponding author.Gingerols represent the main bioactive compounds in ginger drugs mostly Zinigiber officinale (F. Zingebraceae) and account for the biological activities and the strong/pungent flavor in ginger. Ginger (Z. officinale) rhizome is one of the most valued herbal drugs for ailments’ treatment in many ayurvedic medicine asides from its culinary applications as a spice. Gingerols and their dehydrated products shogaols are phenolic phytochemicals found in members of the Zingiberaceae family and account for most of their effects including anti-inflammatory and anticancer activities. This review entails most of the novel trends related to the extraction, optimization, and formulations of gingerols and shogaols to insure best recoveries and efficacies from their natural resources. Further, it presents a comprehensive overview of the different analytical approaches for the determination of gingerols/shogaols’ levels in nutraceuticals to ensure highest quality and for their detection in body fluids for proof of efficacy.http://www.sciencedirect.com/science/article/pii/S2590157523003905GingerolsGingerExtractionFormulationsAntioxidantShogaols |
| spellingShingle | Yasmin R. Maghraby Rola M. Labib Mansour Sobeh Mohamed A. Farag Gingerols and shogaols: A multi-faceted review of their extraction, formulation, and analysis in drugs and biofluids to maximize their nutraceutical and pharmaceutical applications Food Chemistry: X Gingerols Ginger Extraction Formulations Antioxidant Shogaols |
| title | Gingerols and shogaols: A multi-faceted review of their extraction, formulation, and analysis in drugs and biofluids to maximize their nutraceutical and pharmaceutical applications |
| title_full | Gingerols and shogaols: A multi-faceted review of their extraction, formulation, and analysis in drugs and biofluids to maximize their nutraceutical and pharmaceutical applications |
| title_fullStr | Gingerols and shogaols: A multi-faceted review of their extraction, formulation, and analysis in drugs and biofluids to maximize their nutraceutical and pharmaceutical applications |
| title_full_unstemmed | Gingerols and shogaols: A multi-faceted review of their extraction, formulation, and analysis in drugs and biofluids to maximize their nutraceutical and pharmaceutical applications |
| title_short | Gingerols and shogaols: A multi-faceted review of their extraction, formulation, and analysis in drugs and biofluids to maximize their nutraceutical and pharmaceutical applications |
| title_sort | gingerols and shogaols a multi faceted review of their extraction formulation and analysis in drugs and biofluids to maximize their nutraceutical and pharmaceutical applications |
| topic | Gingerols Ginger Extraction Formulations Antioxidant Shogaols |
| url | http://www.sciencedirect.com/science/article/pii/S2590157523003905 |
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