Clinical utility of circulating tumor DNA profiling in detecting targetable fusions in non-small cell lung cancer

Clinical utility of circulating tumor DNA profiling in detecting targetable fusions in non-small cell lung cancer

IntroductionNumerous studies have suggested high concordance between tissue and circulating tumor DNA (ctDNA) comprehensive genomic profiling (CGP) tests but only few of them focused on fusions. In addition, atypical breakpoints occasionally detected from DNA-based fusion detection make interpretati...

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Bibliographic Details
Main Authors: Young-gon Kim, Boram Lee, Changhee Ha, Cheonghwa Lee, Hyun Ae Jung, Jong-Mu Sun, Se-Hoon Lee, Myung-Ju Ahn, Yoon-La Choi, Sehhoon Park, Jong-Won Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Oncology
Subjects:
circulating-tumor DNA
ctDNA
gene fusion
non-small cell lung cancer
comprehensive genomic profiling
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1463341/full

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https://www.frontiersin.org/articles/10.3389/fonc.2024.1463341/full

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