Esketamine induces embryonic and cardiac malformation through regulating the nkx2.5 and gata4 in zebrafish

Abstract Esketamine (EK) has been widely used in the treatment of depression, but the effects of EK prenatal treatment on embryonic heart development have been rarely reported. This study assesses the effects of varying concentrations of EK on embryonic development and cardiogenesis to determine the...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Shuang Li, Xiang Li, Rui Zhao, Tingyu Jiang, Qiuyun Ou, Huansen Huang, Jiancheng Tang
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Nature Portfolio 2025-02-01
Σειρά:Scientific Reports
Διαθέσιμο Online:https://doi.org/10.1038/s41598-025-91315-2

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