FGF2 disruption enhances thermogenesis in brown and beige fat to protect against adiposity and hepatic steatosis

FGF2 disruption enhances thermogenesis in brown and beige fat to protect against adiposity and hepatic steatosis

Objective: Fibroblast growth factor 2 (FGF2) has been reported to play divergent roles in white adipogenic differentiation, however, whether it regulates thermogenesis of fat tissues remains largely unknown. We therefore aimed to investigate the effect of FGF2 on fat thermogenesis and elucidate the...

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Hlavní autoři: Haifang Li, Xinzhi Zhang, Cheng Huang, Huan Liu, Qiang Zhang, Qianying Sun, Yanxin Jia, Shuang Liu, Mei Dong, Mengjie Hou, Yiming Liu, Hai Lin
Médium: Článek
Jazyk:English
Vydáno: Elsevier 2021-12-01
Edice:Molecular Metabolism
Témata:
Fibroblast growth factor 2 (FGF2)
Thermogenesis
Brown and beige fat
PPARγ
PGC-1α
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2212877821002052

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http://www.sciencedirect.com/science/article/pii/S2212877821002052

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