Design, Synthesis, Spectroscopic Characterisation and In Vitro Cytostatic Evaluation of Novel Bis(coumarin-1,2,3-triazolyl)benzenes and Hybrid Coumarin-1,2,3-triazolyl-aryl Derivatives

Design, Synthesis, Spectroscopic Characterisation and In Vitro Cytostatic Evaluation of Novel Bis(coumarin-1,2,3-triazolyl)benzenes and Hybrid Coumarin-1,2,3-triazolyl-aryl Derivatives

In this work, a series of novel 1,2,3-triazolyl-coumarin hybrid systems were designed as potential antitumour agents. The structural modification of the coumarin ring was carried out by Cu(I)-catalysed Huisgen 1,3-dipolar cycloaddition of 7-azido-4-methylcoumarin and terminal aromatic alkynes to obt...

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Bibliographische Detailangaben
Hauptverfasser: Kristina Pršir, Ema Horak, Marijeta Kralj, Lidija Uzelac, Sandra Liekens, Ivana Murković Steinberg, Svjetlana Krištafor
Format: Artikel
Sprache:English
Veröffentlicht: MDPI AG 2022-01-01
Schriftenreihe:Molecules
Schlagworte:
coumarin
1,2,3-triazole
benzazole
organic synthesis
cytostatic evaluation
fluorescence
Online Zugang:https://www.mdpi.com/1420-3049/27/3/637

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https://www.mdpi.com/1420-3049/27/3/637

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