The effect of pseudocatalase/superoxide dismutase in the treatment of vitiligo: A pilot study
Objective : Pseudocatalase/superoxide dismutase (PSD) is a topical gel considered having therapeutic effects in vitiligo. This study was designed to evaluate the efficacy of this combination in vitiligo. Methods : This was a pilot randomized, double-blind, placebo-controlled trial on 46 symmetrical...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-01-01
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| Series: | Journal of Research in Pharmacy Practice |
| Subjects: | |
| Online Access: | http://www.jrpp.net/article.asp?issn=2319-9644;year=2012;volume=1;issue=2;spage=77;epage=80;aulast=Naini |
| _version_ | 1818128276165492736 |
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| author | Farahnaz Fatemi Naini Alireza Vaez Shooshtari Bahareh Ebrahimi Razieh Molaei |
| author_facet | Farahnaz Fatemi Naini Alireza Vaez Shooshtari Bahareh Ebrahimi Razieh Molaei |
| author_sort | Farahnaz Fatemi Naini |
| collection | DOAJ |
| description | Objective : Pseudocatalase/superoxide dismutase (PSD) is a topical gel considered having therapeutic effects in vitiligo. This study was designed to evaluate the efficacy of this combination in vitiligo.
Methods : This was a pilot randomized, double-blind, placebo-controlled trial on 46 symmetrical vitiligo lesions of limbs in 23 patients referring to dermatology clinics, Isfahan, Iran in 2010. Patients were received this formula or placebo gels for the right and left lesions. Lesion area and degree of pigmentation were assessed at baseline, 2, 4, and 6 months.
Findings : There were no significant changes in lesion area and perifollicular pigmentation in each group (P > 0.05).
Conclusion : The results indicated no significant therapeutic effect for PSD in vitiligo. |
| first_indexed | 2024-12-11T07:30:40Z |
| format | Article |
| id | doaj.art-dbcb245aab7847329d08361435552b2b |
| institution | Directory Open Access Journal |
| issn | 2319-9644 2279-042X |
| language | English |
| last_indexed | 2024-12-11T07:30:40Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Research in Pharmacy Practice |
| spelling | doaj.art-dbcb245aab7847329d08361435552b2b2022-12-22T01:15:50ZengWolters Kluwer Medknow PublicationsJournal of Research in Pharmacy Practice2319-96442279-042X2012-01-0112778010.4103/2279-042X.108375The effect of pseudocatalase/superoxide dismutase in the treatment of vitiligo: A pilot studyFarahnaz Fatemi NainiAlireza Vaez ShooshtariBahareh EbrahimiRazieh MolaeiObjective : Pseudocatalase/superoxide dismutase (PSD) is a topical gel considered having therapeutic effects in vitiligo. This study was designed to evaluate the efficacy of this combination in vitiligo. Methods : This was a pilot randomized, double-blind, placebo-controlled trial on 46 symmetrical vitiligo lesions of limbs in 23 patients referring to dermatology clinics, Isfahan, Iran in 2010. Patients were received this formula or placebo gels for the right and left lesions. Lesion area and degree of pigmentation were assessed at baseline, 2, 4, and 6 months. Findings : There were no significant changes in lesion area and perifollicular pigmentation in each group (P > 0.05). Conclusion : The results indicated no significant therapeutic effect for PSD in vitiligo.http://www.jrpp.net/article.asp?issn=2319-9644;year=2012;volume=1;issue=2;spage=77;epage=80;aulast=NainiPseudocatalase/superoxide dismutase; efficacy; vitiligo |
| spellingShingle | Farahnaz Fatemi Naini Alireza Vaez Shooshtari Bahareh Ebrahimi Razieh Molaei The effect of pseudocatalase/superoxide dismutase in the treatment of vitiligo: A pilot study Journal of Research in Pharmacy Practice Pseudocatalase/superoxide dismutase; efficacy; vitiligo |
| title | The effect of pseudocatalase/superoxide dismutase in the treatment of vitiligo: A pilot study |
| title_full | The effect of pseudocatalase/superoxide dismutase in the treatment of vitiligo: A pilot study |
| title_fullStr | The effect of pseudocatalase/superoxide dismutase in the treatment of vitiligo: A pilot study |
| title_full_unstemmed | The effect of pseudocatalase/superoxide dismutase in the treatment of vitiligo: A pilot study |
| title_short | The effect of pseudocatalase/superoxide dismutase in the treatment of vitiligo: A pilot study |
| title_sort | effect of pseudocatalase superoxide dismutase in the treatment of vitiligo a pilot study |
| topic | Pseudocatalase/superoxide dismutase; efficacy; vitiligo |
| url | http://www.jrpp.net/article.asp?issn=2319-9644;year=2012;volume=1;issue=2;spage=77;epage=80;aulast=Naini |
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