Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives
Acute short-term noninvasive ventilation (NIV) for hypercapnic respiratory failure in chronic obstructive pulmonary disease (COPD) has well-established benefits; however, the role of long-term home NIV remains controversial. In the past decade, studies utilizing aggressive NIV settings to maximally...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2023-01-01
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| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/2023/8691539 |
| _version_ | 1797662218326638592 |
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| author | Rachel Jen Colin Ellis Marta Kaminska Jeremy Road Najib Ayas |
| author_facet | Rachel Jen Colin Ellis Marta Kaminska Jeremy Road Najib Ayas |
| author_sort | Rachel Jen |
| collection | DOAJ |
| description | Acute short-term noninvasive ventilation (NIV) for hypercapnic respiratory failure in chronic obstructive pulmonary disease (COPD) has well-established benefits; however, the role of long-term home NIV remains controversial. In the past decade, studies utilizing aggressive NIV settings to maximally reduce carbon dioxide levels (PaCO2) have resulted in several positive clinical trials and led to updated guidelines on home NIV for stable hypercapnic COPD patients. This clinical respiratory review discusses the high-intensity NIV approach, summarizes recent key trials and guidelines pertaining to home NIV in COPD, and considers key clinical questions for future research and application in the Canadian context. With recent evidence and Canadian Thoracic Society (CTS) guidelines supporting the use of NIV in carefully selected COPD patients with persistent daytime hypercapnia, we believe it is time to reconsider our approach. |
| first_indexed | 2024-03-11T18:56:57Z |
| format | Article |
| id | doaj.art-dbcccb20e0b64ea9b890f1fd035eb572 |
| institution | Directory Open Access Journal |
| issn | 1916-7245 |
| language | English |
| last_indexed | 2024-03-11T18:56:57Z |
| publishDate | 2023-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj.art-dbcccb20e0b64ea9b890f1fd035eb5722023-10-11T00:00:02ZengHindawi LimitedCanadian Respiratory Journal1916-72452023-01-01202310.1155/2023/8691539Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian PerspectivesRachel Jen0Colin Ellis1Marta Kaminska2Jeremy Road3Najib Ayas4Department of MedicineDepartment of MedicineRespiratory Division and Sleep LaboratoryDepartment of MedicineDepartment of MedicineAcute short-term noninvasive ventilation (NIV) for hypercapnic respiratory failure in chronic obstructive pulmonary disease (COPD) has well-established benefits; however, the role of long-term home NIV remains controversial. In the past decade, studies utilizing aggressive NIV settings to maximally reduce carbon dioxide levels (PaCO2) have resulted in several positive clinical trials and led to updated guidelines on home NIV for stable hypercapnic COPD patients. This clinical respiratory review discusses the high-intensity NIV approach, summarizes recent key trials and guidelines pertaining to home NIV in COPD, and considers key clinical questions for future research and application in the Canadian context. With recent evidence and Canadian Thoracic Society (CTS) guidelines supporting the use of NIV in carefully selected COPD patients with persistent daytime hypercapnia, we believe it is time to reconsider our approach.http://dx.doi.org/10.1155/2023/8691539 |
| spellingShingle | Rachel Jen Colin Ellis Marta Kaminska Jeremy Road Najib Ayas Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives Canadian Respiratory Journal |
| title | Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives |
| title_full | Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives |
| title_fullStr | Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives |
| title_full_unstemmed | Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives |
| title_short | Noninvasive Home Mechanical Ventilation for Stable Hypercapnic COPD: A Clinical Respiratory Review from Canadian Perspectives |
| title_sort | noninvasive home mechanical ventilation for stable hypercapnic copd a clinical respiratory review from canadian perspectives |
| url | http://dx.doi.org/10.1155/2023/8691539 |
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