Deciphering the mechanism of action of VP343, an antileishmanial drug candidate, in Leishmania infantum
Summary: Antileishmanial chemotherapy is currently limited due to severe toxic side effects and drug resistance. Hence, new antileishmanial compounds based on alternative approaches, mainly to avoid the emergence of drug resistance, are needed. The present work aims to decipher the mechanism of acti...
Prif Awduron: | Sameh Obeid, Eloisa Berbel-Manaia, Valérie Nicolas, Indira Dennemont, Julien Barbier, Jean-Christophe Cintrat, Daniel Gillet, Philippe M. Loiseau, Sébastien Pomel |
---|---|
Fformat: | Erthygl |
Iaith: | English |
Cyhoeddwyd: |
Elsevier
2023-11-01
|
Cyfres: | iScience |
Pynciau: | |
Mynediad Ar-lein: | http://www.sciencedirect.com/science/article/pii/S2589004223022216 |
Eitemau Tebyg
-
Antileishmanial activity of terpenylquinones on Leishmania infantum and their effects on Leishmania topoisomerase IB
gan: Yolanda Pérez-Pertejo, et al.
Cyhoeddwyd: (2019-12-01) -
Leishmania infantum asymptomatic infection in inflammatory bowel disease patients under anti-TNF therapy
gan: M. Carmen Guillén, et al.
Cyhoeddwyd: (2020-05-01) -
Leishmania amazonensis sabotages host cell SUMOylation for intracellular survival
gan: Kendi Okuda, et al.
Cyhoeddwyd: (2022-09-01) -
Antileishmanial Activity of BNIPDaoct- and BNIPDanon-loaded Emulsomes on Leishmania infantum Parasites
gan: Zeynep Islek, et al.
Cyhoeddwyd: (2022-01-01) -
The different impact of drug-resistant Leishmania on the transcription programs activated in neutrophils
gan: Míriam Díaz-Varela, et al.
Cyhoeddwyd: (2024-05-01)