Deciphering the mechanism of action of VP343, an antileishmanial drug candidate, in Leishmania infantum

Deciphering the mechanism of action of VP343, an antileishmanial drug candidate, in Leishmania infantum

Summary: Antileishmanial chemotherapy is currently limited due to severe toxic side effects and drug resistance. Hence, new antileishmanial compounds based on alternative approaches, mainly to avoid the emergence of drug resistance, are needed. The present work aims to decipher the mechanism of acti...

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Dettagli Bibliografici
Autori principali:	Sameh Obeid, Eloisa Berbel-Manaia, Valérie Nicolas, Indira Dennemont, Julien Barbier, Jean-Christophe Cintrat, Daniel Gillet, Philippe M. Loiseau, Sébastien Pomel
Natura:	Articolo
Lingua:	English
Pubblicazione:	Elsevier 2023-11-01
Serie:	iScience
Soggetti:	Parasitology Drugs Cell biology
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2589004223022216

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