Trends in <i>Pseudomonas aeruginosa</i> (<i>P. aeruginosa</i>) Bacteremia during the COVID-19 Pandemic: A Systematic Review
<i>Pseudomonas aeruginosa</i> (<i>P. aeruginosa</i>) is among the most common pathogens associated with healthcare-acquired infections, and is often antibiotic resistant, causing significant morbidity and mortality in cases of <i>P. aeruginosa</i> bacteremia. It r...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/12/2/409 |
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| author | Qin Xiang Ng Natasha Yixuan Ong Dawn Yi Xin Lee Chun En Yau Yu Liang Lim Andrea Lay Hoon Kwa Ban Hock Tan |
| author_facet | Qin Xiang Ng Natasha Yixuan Ong Dawn Yi Xin Lee Chun En Yau Yu Liang Lim Andrea Lay Hoon Kwa Ban Hock Tan |
| author_sort | Qin Xiang Ng |
| collection | DOAJ |
| description | <i>Pseudomonas aeruginosa</i> (<i>P. aeruginosa</i>) is among the most common pathogens associated with healthcare-acquired infections, and is often antibiotic resistant, causing significant morbidity and mortality in cases of <i>P. aeruginosa</i> bacteremia. It remains unclear how the incidence of <i>P. aeruginosa</i> bacteremia changed during the Coronavirus Disease 2019 (COVID-19) pandemic, with studies showing almost contradictory conclusions despite enhanced infection control practices during the pandemic. This systematic review sought to examine published reports with incidence rates for <i>P. aeruginosa</i> bacteremia during (defined as from March 2020 onwards) and prior to the COVID-19 pandemic. A systematic literature search was conducted in accordance with PRISMA guidelines and performed in Cochrane, Embase, and Medline with combinations of the key words (pseudomonas aeruginosa OR PAE) AND (incidence OR surveillance), from database inception until 1 December 2022. Based on the pre-defined inclusion criteria, a total of eight studies were eligible for review. Prior to the pandemic, the prevalence of <i>P. aeruginosa</i> was on an uptrend. Several international reports found a slight increase in the incidence of <i>P. aeruginosa</i> bacteremia during the COVID-19 pandemic. These findings collectively highlight the continued importance of good infection prevention and control and antimicrobial stewardship during both pandemic and non-pandemic periods. It is important to implement effective infection prevention and control measures, including ensuring hand hygiene, stepping up environmental cleaning and disinfection efforts, and developing timely guidelines on the appropriate prescription of antibiotics. |
| first_indexed | 2024-03-11T09:15:26Z |
| format | Article |
| id | doaj.art-dbd0b26cbf914f5a90c2566c01a64b14 |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-11T09:15:26Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-dbd0b26cbf914f5a90c2566c01a64b142023-11-16T18:44:40ZengMDPI AGAntibiotics2079-63822023-02-0112240910.3390/antibiotics12020409Trends in <i>Pseudomonas aeruginosa</i> (<i>P. aeruginosa</i>) Bacteremia during the COVID-19 Pandemic: A Systematic ReviewQin Xiang Ng0Natasha Yixuan Ong1Dawn Yi Xin Lee2Chun En Yau3Yu Liang Lim4Andrea Lay Hoon Kwa5Ban Hock Tan6Health Services Research Unit, Singapore General Hospital, Singapore 169608, SingaporeYong Loo Lin School of Medicine, National University of Singapore, 10 Medical Dr, Singapore 117597, SingaporeSchool of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow G12 8QQ, UKYong Loo Lin School of Medicine, National University of Singapore, 10 Medical Dr, Singapore 117597, SingaporeMOH Holdings Pte Ltd., 1 Maritime Square, Singapore 099253, SingaporeDepartment of Pharmacy, Singapore General Hospital, Singapore 169608, SingaporeDepartment of Infectious Diseases, Singapore General Hospital, Singapore 169608, Singapore<i>Pseudomonas aeruginosa</i> (<i>P. aeruginosa</i>) is among the most common pathogens associated with healthcare-acquired infections, and is often antibiotic resistant, causing significant morbidity and mortality in cases of <i>P. aeruginosa</i> bacteremia. It remains unclear how the incidence of <i>P. aeruginosa</i> bacteremia changed during the Coronavirus Disease 2019 (COVID-19) pandemic, with studies showing almost contradictory conclusions despite enhanced infection control practices during the pandemic. This systematic review sought to examine published reports with incidence rates for <i>P. aeruginosa</i> bacteremia during (defined as from March 2020 onwards) and prior to the COVID-19 pandemic. A systematic literature search was conducted in accordance with PRISMA guidelines and performed in Cochrane, Embase, and Medline with combinations of the key words (pseudomonas aeruginosa OR PAE) AND (incidence OR surveillance), from database inception until 1 December 2022. Based on the pre-defined inclusion criteria, a total of eight studies were eligible for review. Prior to the pandemic, the prevalence of <i>P. aeruginosa</i> was on an uptrend. Several international reports found a slight increase in the incidence of <i>P. aeruginosa</i> bacteremia during the COVID-19 pandemic. These findings collectively highlight the continued importance of good infection prevention and control and antimicrobial stewardship during both pandemic and non-pandemic periods. It is important to implement effective infection prevention and control measures, including ensuring hand hygiene, stepping up environmental cleaning and disinfection efforts, and developing timely guidelines on the appropriate prescription of antibiotics.https://www.mdpi.com/2079-6382/12/2/409<i>P. aeruginosa</i>COVID-19collateral effectantibioticsantimicrobial stewardship |
| spellingShingle | Qin Xiang Ng Natasha Yixuan Ong Dawn Yi Xin Lee Chun En Yau Yu Liang Lim Andrea Lay Hoon Kwa Ban Hock Tan Trends in <i>Pseudomonas aeruginosa</i> (<i>P. aeruginosa</i>) Bacteremia during the COVID-19 Pandemic: A Systematic Review Antibiotics <i>P. aeruginosa</i> COVID-19 collateral effect antibiotics antimicrobial stewardship |
| title | Trends in <i>Pseudomonas aeruginosa</i> (<i>P. aeruginosa</i>) Bacteremia during the COVID-19 Pandemic: A Systematic Review |
| title_full | Trends in <i>Pseudomonas aeruginosa</i> (<i>P. aeruginosa</i>) Bacteremia during the COVID-19 Pandemic: A Systematic Review |
| title_fullStr | Trends in <i>Pseudomonas aeruginosa</i> (<i>P. aeruginosa</i>) Bacteremia during the COVID-19 Pandemic: A Systematic Review |
| title_full_unstemmed | Trends in <i>Pseudomonas aeruginosa</i> (<i>P. aeruginosa</i>) Bacteremia during the COVID-19 Pandemic: A Systematic Review |
| title_short | Trends in <i>Pseudomonas aeruginosa</i> (<i>P. aeruginosa</i>) Bacteremia during the COVID-19 Pandemic: A Systematic Review |
| title_sort | trends in i pseudomonas aeruginosa i i p aeruginosa i bacteremia during the covid 19 pandemic a systematic review |
| topic | <i>P. aeruginosa</i> COVID-19 collateral effect antibiotics antimicrobial stewardship |
| url | https://www.mdpi.com/2079-6382/12/2/409 |
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