Nicotinamide adenine dinucleotide supplementation drives gut microbiota variation in Alzheimer’s mouse model

Nicotinamide adenine dinucleotide supplementation drives gut microbiota variation in Alzheimer’s mouse model

Alzheimer’s disease (AD) is the most common neurodegenerative disease. Growing evidence suggests an important role for gut dysbiosis and gut microbiota-host interactions in aging and neurodegeneration. Our previous works have demonstrated that supplementation with the nicotinamide adenine dinucleoti...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Xixia Chu, Yujun Hou, Qiong Meng, Deborah L. Croteau, Yong Wei, Supriyo De, Kevin G. Becker, Vilhelm A. Bohr
Format:	Article
Sprog:	English
Udgivet:	Frontiers Media S.A. 2022-09-01
Serier:	Frontiers in Aging Neuroscience
Fag:	Alzheimer’s disease nicotinamide riboside gut microbiome APP/PS1 transgenic mice neuroinflammation aging
Online adgang:	https://www.frontiersin.org/articles/10.3389/fnagi.2022.993615/full

Lignende værker

Urolithin A and nicotinamide riboside differentially regulate innate immune defenses and metabolism in human microglial cells
af: Helena Borland Madsen, et al.
Udgivet: (2024-11-01)

Nicotinamide riboside modulates the reactive species interactome, bioenergetic status and proteomic landscape in a brain-region-specific manner
af: Alejandro Marmolejo-Garza, et al.
Udgivet: (2024-10-01)

Roles of Nicotinamide Adenine Dinucleotide (NAD+) in Biological Systems
af: Palmiro Poltronieri, et al.
Udgivet: (2018-01-01)

Nicotinamide riboside kinase 1 protects against diet and age-induced pancreatic β-cell failure
af: Angelique Cercillieux, et al.
Udgivet: (2022-12-01)

Nicotinamide adenine dinucleotide is transported into mammalian mitochondria
af: Antonio Davila, et al.
Udgivet: (2018-06-01)

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells
af: Rachel S. Fletcher, et al.
Udgivet: (2017-08-01)

Comparison of protective effects of nicotinamide mononucleotide and nicotinamide riboside on DNA damage induced by cisplatin in HeLa cells
af: Shuting Qiu, et al.
Udgivet: (2024-03-01)

Syntheses and chemical properties of β-nicotinamide riboside and its analogues and derivatives
af: Mikhail V. Makarov, et al.
Udgivet: (2019-02-01)

How to mitigate neurological and cardiac decompensation in Leigh syndrome: Can nicotinamide riboside be an answer?
af: Alessandro Prigione, et al.
Udgivet: (2022-09-01)

The effects of in ovo nicotinamide riboside dose on broiler myogenesis
af: Xiaoxing Xu, et al.
Udgivet: (2021-03-01)

Nicotinamide riboside exerts protective effect against aging-induced NAFLD-like hepatic dysfunction in mice
af: Xue Han, et al.
Udgivet: (2019-08-01)

Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside
af: Sharath Anugula, et al.
Udgivet: (2023-06-01)

The role of nicotinamide adenine dinucleotide salvage enzymes in cardioprotection
af: Fazle Kibria, et al.
Udgivet: (2024-07-01)

Semisynthetic biosensors for mapping cellular concentrations of nicotinamide adenine dinucleotides
af: Olivier Sallin, et al.
Udgivet: (2018-05-01)

Novel insight into nicotinamide adenine dinucleotide and related metabolites in cancer patients undergoing surgery
af: Hiroaki Fujita, et al.
Udgivet: (2024-07-01)

Nicotinamide Riboside Regulates Chemotaxis to Decrease Inflammation and Ameliorate Functional Recovery Following Spinal Cord Injury in Mice
af: Yan Li, et al.
Udgivet: (2024-02-01)

Nicotinamide riboside alleviates exercise intolerance in ANT1-deficient mice
af: Patrick M. Schaefer, et al.
Udgivet: (2022-10-01)

Nicotinamide Riboside and Phycocyanin Oligopeptides Affect Stress Susceptibility in Chronic Corticosterone-Exposed Rats
af: Cemal Orhan, et al.
Udgivet: (2023-10-01)

Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and nicotinamide adenine dinucleotide biosynthesis in healthy, middle-aged Japanese men
af: Shintaro Yamaguchi, et al.
Udgivet: (2024-02-01)

Nicotinamide riboside supplementation ameliorates ovarian dysfunction in a PCOS mouse model
af: Zhenye Zhu, et al.
Udgivet: (2025-01-01)

Progress in research on mechanism of nicotinamide adenine dinucleotide and its precursors against aging-related diseases
af: Shixiong ZHENG, et al.
Udgivet: (2023-06-01)

Nicotinamide Adenine Dinucleotide (NAD) Metabolism as a Relevant Target in Cancer
af: Lola E. Navas, et al.
Udgivet: (2022-08-01)

Extension of use of nicotinamide riboside chloride as a novel food pursuant to Regulation (EU) 2015/2283
af: EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), et al.
Udgivet: (2021-11-01)

Erythrocyte nicotinamide adenine dinucleotide concentration is enhanced by systematic sports participation
af: Barbara Pospieszna, et al.
Udgivet: (2024-10-01)

Navigating Alzheimer’s Disease Mouse Models: Age-Related Pathology and Cognitive Deficits
af: Laura Maria De Plano, et al.
Udgivet: (2024-11-01)

Effects of Nicotinamide Riboside Supplementation on Postmortem Mitochondrial Functionality and Apoptotic Activation
af: Chen Zhu, et al.
Udgivet: (2025-01-01)

Axonal Protection by Oral Nicotinamide Riboside Treatment with Upregulated AMPK Phosphorylation in a Rat Glaucomatous Degeneration Model
af: Ibuki Arizono, et al.
Udgivet: (2023-08-01)

Gastrodin as a multi-target protective compound reverses learning memory deficits and AD-like pathology in APP/PS1 transgenic mice
af: Yue-Qin Zeng, et al.
Udgivet: (2021-02-01)

Rational Design for Improving the Thermostability of Saccharomyces cerevisiae Nicotinamide Riboside Kinase 1
af: WANG Yao, SHEN Taisong, LI Sichen, SHI Hongling, YAO Lunguang, TANG Cunduo
Udgivet: (2024-12-01)

Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3
af: Nahid A Khan, et al.
Udgivet: (2014-04-01)

The effects of nicotinamide adenine dinucleotide in cardiovascular diseases: Molecular mechanisms, roles and therapeutic potential
af: Xiaokai Zhang, et al.
Udgivet: (2022-07-01)

S‐adenosylmethionine and nicotinamide riboside therapy in Arts syndrome: A case report and literature review
af: Angela Lee, et al.
Udgivet: (2023-11-01)

Epithelial NAD+ depletion drives mitochondrial dysfunction and contributes to intestinal inflammation
af: Elizabeth A. Novak, et al.
Udgivet: (2023-09-01)

The Role of NAD<sup>+</sup> in Metabolic Regulation of Adipose Tissue: Implications for Obesity-Induced Insulin Resistance
af: Tatjana Ruskovska, et al.
Udgivet: (2023-09-01)

Nicotinamide adenine dinucleotide phosphate oxidase activation and neuronal death after ischemic stroke
af: Jiamei Shen, et al.
Udgivet: (2019-01-01)

Hepatic steatosis induced by nicotine plus Coca-Cola™ is prevented by nicotinamide riboside (NR)
af: Juan Carlos Rivera, et al.
Udgivet: (2024-05-01)

Nicotinamide adenine dinucleotide treatment confers resistance to neonatal ischemia and hypoxia: effects on neurobehavioral phenotypes
af: Xiaowen Xu, et al.
Udgivet: (2024-01-01)

Nicotinamide riboside first alleviates symptoms but later downregulates dopamine metabolism in proteasome inhibition mouse model of Parkinson's disease
af: Giorgio Turconi, et al.
Udgivet: (2024-07-01)

Pathways Linking Nicotinamide Adenine Dinucleotide Phosphate Production to Endoplasmic Reticulum Protein Oxidation and Stress
af: Erica R. Gansemer, et al.
Udgivet: (2022-05-01)

Effects of NAD+ precursor supplementation on glucose and lipid metabolism in humans: a meta-analysis
af: Ou Zhong, et al.
Udgivet: (2022-03-01)