Dandy–Walker malformation and intermittent explosive disorder: A case report
Dandy–Walker malformation is a group of brain malformations that sometimes present with psychotic features, violent and impulsive behavior, or mood symptoms. Here, we present a case report of a patient with Dandy–Walker malformation who presented with intermittent explosive disorder. A young man, ag...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
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SAGE Publishing
2022-06-01
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Series: | SAGE Open Medical Case Reports |
Online Access: | https://doi.org/10.1177/2050313X221103355 |
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author | Mohamed El Tahir Mai Ahmed Salma Salman Bushra Elhusein |
author_facet | Mohamed El Tahir Mai Ahmed Salma Salman Bushra Elhusein |
author_sort | Mohamed El Tahir |
collection | DOAJ |
description | Dandy–Walker malformation is a group of brain malformations that sometimes present with psychotic features, violent and impulsive behavior, or mood symptoms. Here, we present a case report of a patient with Dandy–Walker malformation who presented with intermittent explosive disorder. A young man, aged 18 years, was brought to the author’s hospital [Hamad Medical Corporation] with anger outbursts, irritable mood, and violent behavior. His magnetic resonance imaging scans showed typical alterations of Dandy–Walker malformation. He also had mild intellectual disabilities and epilepsy. After a few weeks of treatment with sodium valproate 1000 mg/day and risperidone 2 mg/day, his condition improved, and his violent behavior was significantly reduced in 3 months, 6 months, and 1 year of follow-up. There is broad consensus that Dandy–Walker malformation is associated with psychosis and other behavioral abnormalities because of a possible disruption in the prefrontal, thalamic, and cerebellar circuits. The link between Dandy–Walker malformation and intermittent explosive disorder may help us understand this type of brain malformation as a potential psychiatric comorbidity. |
first_indexed | 2024-12-12T04:19:30Z |
format | Article |
id | doaj.art-dbd21377cd7d4ba8aafab0a4439dc014 |
institution | Directory Open Access Journal |
issn | 2050-313X |
language | English |
last_indexed | 2024-12-12T04:19:30Z |
publishDate | 2022-06-01 |
publisher | SAGE Publishing |
record_format | Article |
series | SAGE Open Medical Case Reports |
spelling | doaj.art-dbd21377cd7d4ba8aafab0a4439dc0142022-12-22T00:38:22ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2022-06-011010.1177/2050313X221103355Dandy–Walker malformation and intermittent explosive disorder: A case reportMohamed El Tahir0Mai Ahmed1Salma Salman2Bushra Elhusein3Department of Psychiatry, Hamad Medical Corporation, Doha, QatarNorthern Ontario School of Medicine, Sault Ste. Marie, ON, CanadaHamad Medical Corporation, Doha, QatarAmbulatory Program—Urgent Consultation Service and Consultation Liaison Psychiatry, London Health Sciences Centre (LHSC), Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, CanadaDandy–Walker malformation is a group of brain malformations that sometimes present with psychotic features, violent and impulsive behavior, or mood symptoms. Here, we present a case report of a patient with Dandy–Walker malformation who presented with intermittent explosive disorder. A young man, aged 18 years, was brought to the author’s hospital [Hamad Medical Corporation] with anger outbursts, irritable mood, and violent behavior. His magnetic resonance imaging scans showed typical alterations of Dandy–Walker malformation. He also had mild intellectual disabilities and epilepsy. After a few weeks of treatment with sodium valproate 1000 mg/day and risperidone 2 mg/day, his condition improved, and his violent behavior was significantly reduced in 3 months, 6 months, and 1 year of follow-up. There is broad consensus that Dandy–Walker malformation is associated with psychosis and other behavioral abnormalities because of a possible disruption in the prefrontal, thalamic, and cerebellar circuits. The link between Dandy–Walker malformation and intermittent explosive disorder may help us understand this type of brain malformation as a potential psychiatric comorbidity.https://doi.org/10.1177/2050313X221103355 |
spellingShingle | Mohamed El Tahir Mai Ahmed Salma Salman Bushra Elhusein Dandy–Walker malformation and intermittent explosive disorder: A case report SAGE Open Medical Case Reports |
title | Dandy–Walker malformation and intermittent explosive disorder: A case report |
title_full | Dandy–Walker malformation and intermittent explosive disorder: A case report |
title_fullStr | Dandy–Walker malformation and intermittent explosive disorder: A case report |
title_full_unstemmed | Dandy–Walker malformation and intermittent explosive disorder: A case report |
title_short | Dandy–Walker malformation and intermittent explosive disorder: A case report |
title_sort | dandy walker malformation and intermittent explosive disorder a case report |
url | https://doi.org/10.1177/2050313X221103355 |
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