Colon adenocarcinoma and Birt–Hogg–Dubé syndrome in a young patient: case report and exploration of pathologic implications

Colon adenocarcinoma and Birt–Hogg–Dubé syndrome in a young patient: case report and exploration of pathologic implications

Birt–Hogg–Dubé syndrome (BHD) is an autosomal dominant disorder caused by germline mutations in the folliculin gene (FLCN) that result in the functional loss of the tumor suppressor folliculin. It is classically associated with cutaneous hamartomas, pulmonary cysts with spontaneous pneumothorax, and...

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Hlavní autoři: Grant W. Jirka, Daniel S. Lefler, Jessica Russo, Babar Bashir
Médium: Článek
Jazyk:English
Vydáno: Taylor & Francis Group 2023-12-01
Edice:Cancer Biology & Therapy
Témata:
birt–hogg–dubé syndrome
colorectal cancer
folliculin gene
flcn mutation
wnt signaling
On-line přístup:http://dx.doi.org/10.1080/15384047.2023.2184153

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