Colon adenocarcinoma and Birt–Hogg–Dubé syndrome in a young patient: case report and exploration of pathologic implications

Colon adenocarcinoma and Birt–Hogg–Dubé syndrome in a young patient: case report and exploration of pathologic implications

Birt–Hogg–Dubé syndrome (BHD) is an autosomal dominant disorder caused by germline mutations in the folliculin gene (FLCN) that result in the functional loss of the tumor suppressor folliculin. It is classically associated with cutaneous hamartomas, pulmonary cysts with spontaneous pneumothorax, and...

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Autori principali: Grant W. Jirka, Daniel S. Lefler, Jessica Russo, Babar Bashir
Natura: Articolo
Lingua:English
Pubblicazione: Taylor & Francis Group 2023-12-01
Serie:Cancer Biology & Therapy
Soggetti:
birt–hogg–dubé syndrome
colorectal cancer
folliculin gene
flcn mutation
wnt signaling
Accesso online:http://dx.doi.org/10.1080/15384047.2023.2184153

Accesso online

http://dx.doi.org/10.1080/15384047.2023.2184153

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