Colon adenocarcinoma and Birt–Hogg–Dubé syndrome in a young patient: case report and exploration of pathologic implications

Colon adenocarcinoma and Birt–Hogg–Dubé syndrome in a young patient: case report and exploration of pathologic implications

Birt–Hogg–Dubé syndrome (BHD) is an autosomal dominant disorder caused by germline mutations in the folliculin gene (FLCN) that result in the functional loss of the tumor suppressor folliculin. It is classically associated with cutaneous hamartomas, pulmonary cysts with spontaneous pneumothorax, and...

Полное описание

Библиографические подробности
Главные авторы: Grant W. Jirka, Daniel S. Lefler, Jessica Russo, Babar Bashir
Формат: Статья
Язык:English
Опубликовано: Taylor & Francis Group 2023-12-01
Серии:Cancer Biology & Therapy
Предметы:
birt–hogg–dubé syndrome
colorectal cancer
folliculin gene
flcn mutation
wnt signaling
Online-ссылка:http://dx.doi.org/10.1080/15384047.2023.2184153

Internet

http://dx.doi.org/10.1080/15384047.2023.2184153

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