Inhibition of LC3-associated phagocytosis in COPD and in response to cigarette smoke

Introduction/Rationale: In chronic obstructive pulmonary disease (COPD), defective macrophage phagocytic clearance of cells undergoing apoptosis by efferocytosis may lead to secondary necrosis of the uncleared cells and contribute to airway inflammation. The precise mechanisms for this phenomenon re...

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Autori principali: Patrick F. Asare, Hai B. Tran, Plinio R. Hurtado, Griffith B. Perkins, Phan Nguyen, Hubertus Jersmann, Eugene Roscioli, Sandra Hodge
Natura: Articolo
Lingua:English
Pubblicazione: SAGE Publishing 2021-10-01
Serie:Therapeutic Advances in Respiratory Disease
Accesso online:https://doi.org/10.1177/17534666211039769