The Effect of the Canine ABCB1‐1Δ Mutation on Sedation after Intravenous Administration of Acepromazine

The Effect of the Canine ABCB1‐1Δ Mutation on Sedation after Intravenous Administration of Acepromazine

Background Dog breeds with the ABCB1‐1Δ mutation have substantially truncated nonfunctional P‐glycoprotein. Dogs homozygous for this mutation (mut/mut) are susceptible to the toxic adverse effects of ivermectin, loperamide, and vincristine. Anecdotal reports suggested ABCB1 mut/mut dogs showed incre...

Detaylı Bibliyografya
Asıl Yazarlar:	D. Deshpande, K.E. Hill, K.L. Mealey, J.P. Chambers, M.A. Gieseg
Materyal Türü:	Makale
Dil:	English
Baskı/Yayın Bilgisi:	Wiley 2016-03-01
Seri Bilgileri:	Journal of Veterinary Internal Medicine
Konular:	Collie MDR1 P‐glycoprotein
Online Erişim:	https://doi.org/10.1111/jvim.13827

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