Effects of CYP3A4*22 and POR*28 variations on the pharmacokinetics of tacrolimus in renal transplant recipients: a meta-analysis of 18 observational studies
Abstract Purpose This study aimed to investigate the association between cytochrome P450 (CYP) 3A4*22 and cytochrome P450 oxidoreductase (POR)*28 variations and the pharmacokinetics of tacrolimus. Methods Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science (SCI), MEDLINE, and Em...
Main Authors: | Ze Li, Xiaozhen Wang, Dandan Li, Sheng Cheng, Zhe Li, Heng Guo, Yiwen Dong, Yingming Zheng, Xingang Li |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-02-01
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Series: | BMC Nephrology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12882-024-03467-4 |
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